Results 121 to 130 of about 18,424 (327)

Study of microstructure and mechanical properties and residual stresses of 24CrNiMo steel prepared by selective laser melting and laser melting deposition

Journal of Materials Research and Technology
Selective laser melting (SLM) and laser direct metal deposition (LMD) have shown promise in advanced manufacturing. However, limited research fabricating the same material using these methods, particularly regarding mechanical properties and residual ...
Yongsheng Zhao, Ying Wu, Dengwen Hu, Yuhua Cai, Yan Liu, Hui Chen   +5 more
doaj   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Dual‐Modulated Vertically Stacked Transistors With Fully Laminated Plate‐Type Architecture Featuring Nanoscale Channel Length

Advanced Science, EarlyView.
A new vertical transistor design with a dual‐modulation strategy is proposed to overcome the limitations of conventional transistors. This architecture uses a micro‐hole patterned electrode and a graphene electrode to enhance channel control and incorporates a leakage blocking layer to suppress off‐state current.
Goeun Pyo, Su Jin Heo, Jeonggyun Jang, Hongki Kang, Byeongmoon Lee, Hyuk‐Jun Kwon, Jae Eun Jang   +6 more
wiley   +1 more source

Growth of tin hillock and whisker under harmonic power conditions in tin-plated copper busbars for power system

Journal of Materials Research and Technology
Tin hillock and whisker growth pose a serious reliability concern in tin-coated copper busbars, particularly in lead-free systems subjected to dynamic electrical environments. In this study, the influence of harmonic current stress on hillock and whisker
Tzu-Sen Su, Wei-Jun Lin, Yen-Chin Huang, Chia-Ming Chang, Tse-I Yeh, Wen-Ting Wu, Cheng-Chien Kuo, Tzu-Sou Chuang, Yung-Ti Hung, Tien-Tze Hsu, Ming-Che Wu, Chih-Hsien Feng, Kuo-Lun Tung, Chao-Hsien Chen, Ming-Da Yang, Yin-Li Su   +15 more
doaj   +1 more source

Effect of long-term stress relief annealing on properties of low-alloy weld deposit of covered electrodes for welding of thick-walled nuclear constructions [PDF]

, 2012
J. Niagaj
openalex   +1 more source

Application of Alloy 718 in M-1 engine components [PDF]

Alloy 718 applied to components of M-1 rocket ...
Frick, V., Hunt, V., Inouye, F. T., Janser, G. R.   +3 more
core   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Investigation of residual stress influence on fatigue crack growth in remanufactured titanium alloy with inhomogeneous microstructure

Journal of Materials Research and Technology
Laser remanufacturing technology is now the top choice for remanufacturing key components of aero-engines because of its cost-effectiveness, resource utilization, and performance recovery.
Xiaohong Zhan, Wanli Ling, Xiaoping Wang, Qiyu Gao, Lijun Liu   +4 more
doaj   +1 more source

Astrocytic TIA1‐Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model

Advanced Science, EarlyView.
Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang, Xin Hua, Ziwei Fan, Jiaxin Zhao, Yuan Zhang, Qiaoyi Zhang, Xi Qu, Shengli Pan, Bingbing Wan, Shiyin Yang, Jia Li, Xu Zhang   +11 more
wiley   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source