Results 81 to 90 of about 2,436,095 (306)

Dynamics of change in rat arterial pressure under conditions of immobilization [PDF]

Emotional stress developed in immobilized rats was shown to be accompanied by changes in the regulation of arterial pressure and the frequency of cardiac contractions.
Ivanona, L. I., Skotselyas, Y. G., Yumatov, Y. A.   +2 more
core   +1 more source

Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction [PDF]

, 2010
Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance.
Adenuga, Adenuga, Barnes, David Adenuga, Garbin, Goven, Harju, Hew, Hongwei Yao, Irfan Rahman, Isaac K. Sundar, Ito, Ito, Itoh, Jae-Woong Hwang, Jaiswal, Keatings, Kramer, Liu, Malhotra, Marwick, Rahman, Rangasamy, Samuel Caito, Sangwoon Chung, Southam, Sun, Tomaki, Trivedi, Yang, Yang, Yao, Yao, Zimmermann   +33 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Functional Characterization of Ammonium Transporter LjAMT2;4 During Lotus japonicus Symbiosis with Rhizobia and Arbuscular Mycorrhizal Fungi

Journal of Fungi
Arbuscular mycorrhizal fungi (AMF) and rhizobia are important symbiotic microorganisms in soil, which can symbiose with legumes to form mycorrhizal symbionts and nodules, respectively.
Kailing Xie, Ying Ni, Lijie Bai, Yuqian Zhai, Wenqing Zhou, Beijiu Cheng, Xiaoyu Li   +6 more
doaj   +1 more source

Breeding for resistance to insect-transmitted viruses in barley – an emerging challenge due to global warming

Journal für Kulturpflanzen, 2009
Due to global warming longer periods of higher temperature in autumn and winter are expected which may result in an increasing importance of insect-transmitted viruses.
Antje Habekuß, Christine Riedel, Edgar Schliephake, Frank Ordon   +3 more
doaj   +1 more source

The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance

, 2019
Misfolded proteins in the endoplasmic reticulum (ER) activate the unfolded protein response (U PR), which enhances protein folding to restore homeostasis.
Aviram, Barlowe, Berner, Bicknell, Bonilla, Boos, Bosis, Braakman, Chen, Christiano, Conz, Cox, Cox, Cox, Dohmen, Finger, Foresti, Foresti, Gasch, Gething, Goldberg, Görner, Hahn, Hahn, Hahn, Hallstrom, Hampton, Hanssum, Hao, Harbison, Higuchi-Sanabria, Hitchcock, Ho, Hou, Huebert, Itzhak, Janke, Jelinsky, Jonikas, Kawaguchi, Khmelinskii, Kim, Knop, Kostova, Leber, Lee, Liu, Longtine, Mannhaupt, Martínez-Pastor, Meiners, Metzger, Mitsiades, Mumberg, Nasmyth, Ng, Ng, Nishitoh, Obeng, Owsianik, Patil, Pincus, Pincus, Prasad, Radhakrishnan, Rapoport, Rousseau, Schuck, Sikorski, Spear, Spear, Sprouffske, Steffen, Stirling, Szoradi, Tkach, Travers, Tyanova, Verghese, Vogel, Walter, Wang, Wang, Wrobel, Xie, Yamamoto, Young, Zheng   +87 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Genome-Wide Identification, Characterization, and Expression Profile of SWEETs Gene Family in Grapevine (Vitis vinifera L.)

Horticulturae
SWEET (Sugars Will Eventually Be Exported Transporter) proteins, identified recently as a novel class of sugar transporters, play pivotal roles in the transport and distribution of photosynthetic products in plants.
Linjing Zhong, Shuya Xu, Chenchen Song, Ning Zhao, Zhiqi Yang, Yanxiang Liu, Xiaoyue Cui, Jianxia Zhang, Zhi Li, Xiping Wang, Min Gao   +10 more
doaj   +1 more source

Environmental protection of titanium alloys at high temperatures [PDF]

Various concepts were evaluated for protecting titanium alloys from oxygen contamination at 922 K (1200 F) and from hot-salt stress-corrosion at 755 K (900 F).
Seltzer, M. S., Wood, R. A., Wright, I. G.   +2 more
core   +1 more source