Results 41 to 50 of about 203,873 (264)
Geofluids, 2021 Rock stress sensitivity is typically investigated macroscopically. In contrast, a new method combining in situ Scanning Electronic Microscope (SEM) study and digital core deformation simulation is developed in this paper, providing an effective way to ...
Weibo Sui, Yanan Hou, Zhilin Cheng
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Generalized optimizations of two-stage forging of micro/meso copper fastener
MATEC Web of Conferences, 2018 Three are generalized simulation optimizations considering the forging force, the die stress, and the dual-goals in two-stage forging of micro/meso copper fastener.
Lin Shih-Hsien +3 more
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A Study on Temperature and Stress Distribution in a Lens under Multi-Stage Cooling Conditions in Progressive Glass Molding Processes [PDF]
한국정밀공학회지Glass Molding Process (GMP) is an effective method for producing precise optical elements such as lenses. This simulation study aimed to predict the distribution of temperature and stress within a lens during a multi-stage cooling process of GMP.
Ji Hyun Hong +5 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
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FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
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Simulated Stress and Stretch of SWCNT
, 2004 7 pages - two columns, 2 tables, 8 figures Published in Proceedings of SIMS 2004, pp.273-279, Editors: Brian Elmegaard, Jon Sporring, Kenny Erleben, Kim ...
Proykova, Ana, Iliev, Hristo
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
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