Results 91 to 100 of about 4,522,899 (285)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Comprehensive analysis of Brassica napus Glycosyl hydrolase family 1 genes and functional analysis of BnaBGLU27.C08 in clubroot resistance

open access: yesBMC Genomics
Background β-Glycosidases (BGLUs), belonging to the Glycoside Hydrolase Family 1 (GH1), play crucial roles in plant growth, development, and stress adaptation. While BGLUs have been extensively characterized in various plants, a comprehensive analysis of
Yiji Shi   +14 more
doaj   +1 more source

Cyclic Loading and Fabric Evolution in Sand: A Constitutive Investigation [PDF]

open access: yes, 2015
An anisotropic plasticity model is proposed to describe the effect of fabric and fabric evolution on the cyclic behaviour of sand within the framework of anisotropic critical state theory.
Gao, Zhiwei, Zhao, Jidong
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Analysis of the grape (Vitis vinifera L.) thaumatin-like protein (TLP) gene family and demonstration that TLP29 contributes to disease resistance

open access: yesScientific Reports, 2017
Thaumatin-like protein (TLP) is present as a large family in plants, and individual members play different roles in various responses to biotic and abiotic stresses.
Xiaoxiao Yan   +6 more
doaj   +1 more source

Bounds on internal state variables in viscoplasticity [PDF]

open access: yes
A typical viscoplastic model will introduce up to three types of internal state variables in order to properly describe transient material behavior; they are as follows: the back stress, the yield stress, and the drag strength.
Freed, Alan D.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Wind stress and its dependence on wind speed and sea state [PDF]

open access: yes, 1992
The aim of the project is to detect and quantify the effect of sea state on the wind stress. An overview of the basic theory of wind stress in the surface layer is provided, along with a more detailed description of the inertial dissipation method which ...
Yelland, M.J.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Universal relationship in gene-expression changes for cells in steady-growth state

open access: yes, 2014
Cells adapt to different conditions by altering a vast number of components, which is measurable using transcriptome analysis. Given that a cell undergoing steady growth is constrained to sustain each of its internal components, the abundance of all the ...
Furusawa, Chikara   +2 more
core   +2 more sources

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