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Generation and Analysis of Transcriptomics Data
2010Transcript profiling ("Transcriptomics") is a widely used technique that obtains information on the abundance of multiple mRNA transcripts within a biological sample simultaneously. Therefore, when a number of such samples are analysed, as in a scientific experiment, large and complex data sets are gene-rated.
Philip D, Glaves, Jonathan D, Tugwood
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Large-Scale Transcriptome Analysis
2017Genomic variants identified to be linked with complex traits such as blood pressure are fewer in coding sequences compared to noncoding sequences. This being the case, there is an increasing need to query the expression of genes at a genome scale to then correlate the cause of alteration in expression to the function of variants regardless of where ...
David, Weaver +2 more
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2013
Transcriptome coexpression analysis is an excellent tool for predicting the physiological functions of genes. It is based on the "guilt-by-association" principle. Generally, genes involved in certain metabolic processes are coordinately regulated. In other words, coexpressed genes tend to be involved in common or closely related biological processes ...
Keiko, Yonekura-Sakakibara +1 more
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Transcriptome coexpression analysis is an excellent tool for predicting the physiological functions of genes. It is based on the "guilt-by-association" principle. Generally, genes involved in certain metabolic processes are coordinately regulated. In other words, coexpressed genes tend to be involved in common or closely related biological processes ...
Keiko, Yonekura-Sakakibara +1 more
openaire +2 more sources
Transcriptome Assembly and Alternative Splicing Analysis
2014Alternative Splicing (AS) is the molecular phenomenon whereby multiple transcripts are produced from the same gene locus. As a consequence, it is responsible for the expansion of eukaryotic transcriptomes. Aberrant AS is involved in the onset and progression of several human diseases.
BONIZZONI, PAOLA +5 more
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Bioinformatics Pipeline for Transcriptome Sequencing Analysis
2016The development of High Throughput Sequencing (HTS) for RNA profiling (RNA-seq) has shed light on the diversity of transcriptomes. While RNA-seq is becoming a de facto standard for monitoring the population of expressed transcripts in a given condition at a specific time, processing the huge amount of data it generates requires dedicated bioinformatics
Djebali, Sarah +5 more
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Analysis of human transcriptomes
Nature Genetics, 1999Victor E Velculescu +33 more
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Distinct transcriptome architectures underlying lupus establishment and exacerbation
Cell, 2022Hiroaki Hatano +2 more
exaly

