Results 1 to 10 of about 1,212,393 (317)

RNA sequence analysis landscape: A comprehensive review of task types, databases, datasets, word embedding methods, and language models

Heliyon
Deciphering information of RNA sequences reveals their diverse roles in living organisms, including gene regulation and protein synthesis. Aberrations in RNA sequence such as dysregulation and mutations can drive a diverse spectrum of diseases including ...
Muhammad Nabeel Asim, Muhammad Ali Ibrahim, Tayyaba Asif, Andreas Dengel   +3 more
doaj   +1 more source

DNApi: A De Novo Adapter Prediction Algorithm for Small RNA Sequencing Data. [PDF]

PLoS ONE, 2016
With the rapid accumulation of publicly available small RNA sequencing datasets, third-party meta-analysis across many datasets is becoming increasingly powerful.
Junko Tsuji, Zhiping Weng
doaj   +1 more source

Identification of novel components of Trypanosoma brucei editosomes [PDF]

, 2003
The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome proteins in Trypanosoma brucei.
Schnaufer, Achim; id_orcid, Wang, Bingbing, Salavati, Reza, Stuart, Kenneth, Carmean, Nicole, Panigrahi, Aswini K, Ernst, Nancy L   +6 more
core   +1 more source

Hypoxia characteristics and prognostic significance of glioblastoma MES-like subpopulation through multi-transcriptomics sequencing

陆军军医大学学报
Objective‍　‍To analyze the composition characteristics and biological functions of tumor cell subpopulations in glioblastoma (GBM) through multi-transcriptomics sequencing technology, and explore the hypoxia characteristics and spatial localization ...
CHEN Tao, YANG Fan, WANG Shuai
doaj   +1 more source

Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry

, 2012
The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest TA family, little is known about
Cook, Gregory M., Mackay, Joel, Cursons, Raymond T., Duyvestyn, Johanna Maria, Mckenzie, Joanna L., Smith, Tony C., Bendak, Katerina, Smith, Tony, Cursons, R. A.Y., Mackay, Joel P., Arcus, Vickery L., Duyvestyn, Johanna M., McKenzie, Joanna Leigh, https://orcid.org/   +13 more
core   +1 more source

Protocol for identifying differentially expressed genes using the RumBall RNA-seq analysis platform

STAR Protocols
Summary: Here, we present a protocol for the identification of differentially expressed genes through RNA sequencing analysis. Starting with FASTQ files from public datasets, this protocol leverages RumBall within a self-contained Docker system.
Luis Augusto Eijy Nagai, Seohyun Lee, Ryuichiro Nakato   +2 more
doaj   +1 more source

Metagenomic Analysis of Marigold: Mixed Infection Including Two New Viruses

Viruses, 2021
Marigold plants with symptoms of mosaic, crinkle, leaf curl and necrosis were observed and small RNA and ribo-depleted total RNA deep sequencing were conducted to identify the associated viruses.
Hang Yin, Zheng Dong, Xulong Wang, Shuhao Lu, Fei Xia, Annihaer Abuduwaili, Yang Bi, Yongqiang Li   +7 more
doaj   +1 more source

A comprehensive comparison of comparative RNA structure prediction approaches

, 2004
Gardner PP, Giegerich R. A comprehensive comparison of comparative RNA structure prediction approaches. BMC Bioinformatics. 2004;5(1): 140.Background: An increasing number of researchers have released novel RNA structure analysis and prediction ...
Giegerich, R., Gardner, Paul P., Gardner, P. P., Paul P Gardner, Robert Giegerich, Giegerich, Robert, Giegerich Robert, Gardner Paul P   +7 more
core   +1 more source

Algorithms for Nucleic Acid Sequence Design [PDF]

, 2010
Motivated by a growing field of research focused on programming function into biomolecules, we seek to decrease the cost of high-quality rational nucleic acid sequence design while increasing its versatility and availability.
Zadeh, Joseph N.
core   +1 more source

A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer’s Disease

Frontiers in Neuroscience, 2020
Potential pathogenic factors, other than well-known APP, APOE4, and PSEN, can be further identified from transcriptomics studies of differentially expressed genes (DEGs) that are specific for Alzheimer’s disease (AD), but findings are often inconsistent ...
Sze Chung Yuen, Hongmei Zhu, Siu-wai Leung, Siu-wai Leung   +3 more
doaj   +1 more source