Results 11 to 20 of about 397,925 (266)

Transcriptomic Analysis of Rat Macrophages [PDF]

open access: yesFrontiers in Immunology, 2021
The laboratory rat is widely used as a model for human diseases. Many of these diseases involve monocytes and tissue macrophages in different states of activation. Whilst methods forin vitrodifferentiation of mouse macrophages from embryonic stem cells (ESC) and bone marrow (BM) are well established, these are lacking for the rat.
Clare Pridans   +6 more
openaire   +5 more sources

Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring

open access: yesJournal of Fungi, 2021
Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood
François Danion   +11 more
doaj   +1 more source

The Redox Homeostasis of Skeletal Muscle Cells Regulates Stage Differentiation of Toxoplasma gondii

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Toxoplasma gondii is an obligatory intracellular parasite that causes persistent infections in birds and mammals including ~30% of the world’s human population.
Md. Taibur Rahman   +8 more
doaj   +1 more source

Transcriptome analysis of human mammary epithelial cells treated with bisphenol A and bisphenol A analogue mixtures reveals major alterations in multiple cellular pathways

open access: yesPublic Health and Toxicology, 2022
Introduction Bisphenol A (BPA) is used in the manufacture of polycarbonate plastics and resins employed in the packaging of food, drink and other products.
Robin Mesnage   +2 more
doaj   +1 more source

Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene

open access: yesBMC Genomics, 2020
Background Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases.
Daniela Kajihara   +9 more
doaj   +1 more source

Identification of the transcriptome profile of after mebendazole treatment [PDF]

open access: yesKosin Medical Journal, 2022
Background The scuticociliate Miamiensis avidus is a major pathogenic agent that causes significant economic losses in the flounder aquaculture industry. Many different types of drugs are being tested to control this disease, including mebendazole, which
Hyunsu Kim   +5 more
doaj   +1 more source

Palindrome-mediated Translocations in Humans: A New Mechanistic Model for Gross Chromosomal Rearrangements

open access: yesFrontiers in Genetics, 2016
Palindromic DNA sequences, which can form secondary structures, are widely distributed in the human genome. Although the nature of the secondary structure—single-stranded hairpin or double-stranded cruciform—has been extensively investigated in vitro ...
Hidehito Inagaki   +8 more
doaj   +1 more source

Protein arginine methyltransferase 6 controls erythroid gene expression and differentiation of human CD34+ progenitor cells

open access: yesHaematologica, 2018
Hematopoietic differentiation is driven by transcription factors, which orchestrate a finely tuned transcriptional network. At bipotential branching points lineage decisions are made, where key transcription factors initiate cell type-specific gene ...
Stefanie C. Herkt   +9 more
doaj   +1 more source

An integrative analysis of metabolomics, DNA methylation and RNA-Seq data reveals key genes involved in albino tea 'Haishun 2'

open access: yesBeverage Plant Research, 2022
Albino tea, a type of tea closely associated with the chlorophyll-deficient phenotype is of great interest due to its multiple benefits to human health.
Kang Wei   +13 more
doaj   +1 more source

IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

open access: yesImmunity, Inflammation and Disease, 2018
Introduction Murine hepatic NK cells exhibit adaptive features, with liver‐specific adhesion molecules CXCR6 and CD49a acting as surface markers. Methods We investigated human liver‐resident CXCR6+ and CD49a+ NK cells using RNA sequencing, flow cytometry,
Theresa Hydes   +9 more
doaj   +1 more source

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