Results 191 to 200 of about 22,008,466 (312)

Material Characterization and Stress-State-Dependent Failure Criteria of AASHTO M180 Guardrail Steel: Experimental and Numerical Investigation. [PDF]

Materials (Basel)
Alomari QA, Yosef TY, Bielenberg RW, Faller RK, Negahban M, Zhang Z, Li W, Humphrey BM.   +7 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

One-Channel Wearable Mental Stress State Monitoring System. [PDF]

Sensors (Basel)
Abdul Kader L, Al-Shargie F, Tariq U, Al-Nashash H.   +3 more
europepmc   +1 more source

Finite Element Evaluation of the Effect of Adhesive Creams on the Stress State of Dentures and Oral Mucosa. [PDF]

Appl Bionics Biomech, 2021
Ramakrishnan AN, Röhrle O, Ludtka C, Varghese R, Koehler J, Kiesow A, Schwan S.   +6 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Evaluating the Stress State and the Load-Bearing Fraction as Predicted by an In Vivo Parameter Identification Method for the Abdominal Aorta. [PDF]

Med Sci (Basel)
Karlsson J, Gade JL, Thore CJ, Carlhäll CJ, Engvall J, Stålhand J.   +5 more
europepmc   +1 more source

Anxiogenic Potential of Experimental Sleep Fragmentation Is Duration-Dependent and Mediated via Oxidative Stress State. [PDF]

Oxid Med Cell Longev, 2021
Grubač Ž, Šutulović N, Šuvakov S, Jerotić D, Puškaš N, Macut D, Rašić-Marković A, Simić T, Stanojlović O, Hrnčić D.   +9 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Evaluation of the stress state based on fecal corticosterone metabolite concentrations in captive penguins in Japan. [PDF]

J Vet Med Sci
Itoh M, Kitahara M, Sawayama N, Matsumoto N, Toyotome T, Yamada K.   +5 more
europepmc   +1 more source

Influence of Psychological Nursing Procedure on Negative Emotion, Stress State, Quality of Life and Nursing Satisfaction in Patients with Lung Cancer Radical Operation. [PDF]

Front Surg, 2022
Yu Y, Xia Y, Fan X, Chen Y, Li C, Zhang J.   +5 more
europepmc   +1 more source