Results 81 to 90 of about 4,522,899 (285)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Background Plant Trihelix transcription factors, specifically bind to GT elements and play important roles in plant physiology and development. Wheat is a main cereal crop.
Chengwei Wang +6 more
doaj +1 more source
The influence of consolidation on shear test results [PDF]
Measurements of the yield behaviour of a cohesive bulk solid in the Jenike shear tester are normally done in two steps. First, pre-shearing to a steady state yielding, and secondly, shearing under a lower normal stress to establish the shear stress at ...
Haaker, G.
core +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Recent Advances in Cotton Transformation and Genome Editing Techniques: The Prospects and Challenges
Genetic transformation in cotton facilitates the integration of stress‐resilient traits, contributing to improved abiotic and biotic stress tolerance. Consequently, sustained efforts to optimise transformation and regeneration protocols are critical for ...
Oluwaseun Olayemi Aluko +8 more
doaj +1 more source
Background B-box (BBX) proteins play important roles in plant growth regulation and development including photomorphogenesis, photoperiodic regulation of flowering, and responses to biotic and abiotic stresses.
Abdullah Shalmani +9 more
doaj +1 more source
Рассматривается напряженное состояние криволинейного бруса, ось которого очерчена по дуге окружности. Брус ограничен поверхностями кругового полого цилиндра. Решение поставленной задачи состоит из трех последовательно проводимых задач: выбор поперечного сечения, приближенное решение (основанное на методах сопротивления материалов) и точное решение ...
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

