Results 101 to 110 of about 4,720,489 (310)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Bearing Capacity Assessment for the Mast of Offshore Workover Rig Based on Stress Measurement
The mast bearing capacity is mainly assessed by conventional methods of stress test method or finite element method.The stress test method or finite element method alone presents the issue of incomprehensive rod study and making necessary assumptions ...
Zhang Xiaodong +4 more
doaj
The Impact of Regulatory Stress Tests on Bank Lending and Its Macroeconomic Consequences [PDF]
Falk Bräuning, José L. Fillat
openalex +1 more source
Possible correlation between work-hardening and fatigue-failure [PDF]
Conceptual theory proposes that cyclic hardening due to non-uniform strain and stress amplitudes during testing, especially during the initial application of stress to a specimen, may correlate positively with the ultimate strength of the specimen under ...
Kettunen, P. O., Kocks, U. F.
core +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Application of Hertzian Tests to Measure Stress–Strain Characteristics of Ceramics at Elevated Temperatures [PDF]
Estíbaliz Sánchez‐González +5 more
openalex +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Toward Understanding Normal Craniocervical Rotation Occurring During the Rotation Stress Test for the Alar Ligaments [PDF]
Peter G. Osmotherly +2 more
openalex +1 more source
CRISES WARNING MODEL - STRESS TEST. ALBANIAN CASE [PDF]
Risk is a permanent companion of any business, including also the banks, which have the objective of managing the money entrusted by the depositors. The effectiveness of this management requires safe and profitable transfer of money between the giver and
Doriana Matraku
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

