Results 141 to 150 of about 4,720,489 (310)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Cognitive emotion regulation fails the stress test [PDF]
, 2013 Candace M. Raio +4 more
openalex +1 more source
Ten deg off-axis tensile test for intralaminar shear characterization of fiber composites [PDF]
A combined theoretical and experimental investigation was conducted to assess the suitability of the 10 deg off-axis tensile test specimen for the intralaminar shear characterization of unidirectional composites.
Chamis, C. C., Sinclair, J. H.
core +1 more source
Strain-age cracking in Rene 41 alloy [PDF]
, 1969 Weldability test determines the effects of material and process variables on the occurrence of strain-age cracking, and demonstrates effective and practical means for its reduction.
Prager, M., Thompson, E. G.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Analysis of the DCB test of angle-ply laminates including residual stresses
, 2017 J. De Gracia +3 more
openalex +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Notched and Unnotched Fatigue Behavior of Angle-Ply Graphite/Epoxy Composites [PDF]
The axial fatigue behavior of both notched and unnotched graphite/epoxy composites was studied. In unnotched studies, conducted on a 0/+ or - 30 3S AS/3501 laminate, S-N curves were determined for various stress ratios R using simply supported test ...
Ramani, S. V., Williams, D. P.
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source