Results 241 to 250 of about 4,720,489 (310)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Prognostic relevance of baseline exercise stress test in RYR2-related CPVT. [PDF]

Europace
Kukavica D, Pili G, Trancuccio A, Giannini G, Pergola V, Memmi M, Gambelli P, Marino M, Morini M, Bloise R, Napolitano C, Mazzanti A, Priori SG.   +12 more
europepmc   +1 more source

Ultrasonic testing of stresses with longitudinal wave – experimental application to evaluate truss bridge

, 2011
Jacek Szelążek, P. Gutkiewicz, Sławomir Mackiewicz   +2 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Ten-Second Cold Water Stress Test Differentiates Parkinson's Disease from Multiple System Atrophy: A Cross-Sectional Pilot Study. [PDF]

Biomedicines
Takahashi M, Hagiwara W, Itaya S, Abe K, Maeda T, Inaba A, Orimo S.   +6 more
europepmc   +1 more source

Additional file 5 of Multiomics analysis reveals that chlorogenic acid alleviates heat stress-induced oxidative damage in prepubertal boar testes via the BLVRA-GPX3 pathway: in vivo and in vitro evidence

Shaoxuan Zhang, Dali Wang, Jiajia Qi, Jing Li, Simin Liu, Hao Sun, Shuang Liang, Boxing Sun   +7 more
openalex   +1 more source

STRESS TESTS DA MÁQUINA DE LINGOTAR GUSA DA USINA DA VALLOUREC & SUMITOMO TUBOS DO BRASIL (VSB)

, 2014
Paulo César Lemes de Almeida, Ronnie Lima de Souza, Hélder Sales Rodrigues, Luciana Resende Alvim, Onidio Teixeira Pinto, Thiago André Oliveira, Luciano Gonçalves de Lima   +6 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Cerebrovascular reactivity: a stress test of brain vascular health in moyamoya disease. [PDF]

Brain Commun
Fan AP, Juttukonda MR.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source