Results 171 to 180 of about 2,550,820 (307)

Registered report: Stress testing predictive models of ideological prejudice. [PDF]

PLoS One
Thompson JL, Cassario AL, Vallabha S, Gnall SA, Rice S, Solanki P, Carrillo A, Brandt MJ, Wetherell GA.   +8 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Evaluating Blood Pressure Response Patterns to Exercise Stress Testing. [PDF]

Hypertension
Nene A, Lee D, Agboola O, Herrin J, Onuma OK, Feher A, Miller EJ, Lu Y, Meadows JL, Spatz ES.   +9 more
europepmc   +1 more source

Consequences of preoperative cardiac stress testing-A cohort study. [PDF]

J Clin Anesth, 2023
Pappas MA, Auerbach AD, Kattan MW, Blackstone EH, Rothberg MB, Sessler DI.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evaluating Compliance to Intra-operative Syndesmosis Stress Testing During Ankle Fracture Fixation: Are We Stressing It? [PDF]

Cureus
Rahim AK, Imtiaz H, Durrani A, Oo TP, Barot K, Kouklidis G, Karim A, Sangar A.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Case series of Type 1 Brugada pattern provoked by exercise: a role for diagnostic treadmill stress testing. [PDF]

Eur Heart J Case Rep
Mehta OH, Ambrosio A, Burnell L, Arbour L, Thibert MJ, Krahn AD, Leather R, van Zyl M.   +7 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Prognostic utility of stress perfusion cardiac magnetic resonance in patients with known or suspected coronary artery disease and inconclusive exercise stress testing. [PDF]

Open Heart
Tanvisut N, Kaolawanich Y.
europepmc   +1 more source