Results 181 to 190 of about 2,550,820 (307)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Virtual stress testing: Analyzing endocrine, metabolic, cardiovascular, and psychological responses to the TSST-VR. [PDF]

Neurobiol Stress
Fellinger E, Brandt T, Schittenhelm A, Quarg E, Pröll M, Domes G, Schmidt A.   +6 more
europepmc   +1 more source

A Millifluidic Chamber for Controlled Shear Stress Testing: Application to Microbial Cultures. [PDF]

Ann Biomed Eng, 2023
Biagini F, Botte E, Calvigioni M, De Maria C, Mazzantini D, Celandroni F, Ghelardi E, Vozzi G.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Assessing myocardial microcirculation in post-PCI patients with chest pain and anxiety: a dynamic CT myocardial perfusion study with mental stress testing. [PDF]

BMC Med Imaging
Shan M, Yu X, Li J, Xing A, Sun W, Qu X.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Before the diagnosis: quality of life in patients presenting with chest pain undergoing Bruce protocol stress testing. [PDF]

BMC Cardiovasc Disord
Mourad G, Deka P, Pathak D, Lopez-Vilella R, Klompstra L, Marques-Sule E.   +5 more
europepmc   +1 more source

Preoperative Stress Testing before Non-Cardiac Surgery. [PDF]

Rev Cardiovasc Med, 2023
Dzhioeva O, Tadic M, Belyavskiy E.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Exercise electrocardiography stress testing in suspected angina and non-obstructive coronary arteries. [PDF]

Eur Heart J
Sykes R, Morrow AJ, Stanley B, Ang D, Roditi G, Stobo D, Corcoran D, Lang NN, Mahrous A, Young R, Carrick D, McGeoch R, McEntegart MB, McConnachie A, Sidik NP, Berry C.   +15 more
europepmc   +1 more source