Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
Long-term Survival of Midurethral Mesh Slings for Women with Stress Urinary Incontinence. [PDF]
Laude M +7 more
europepmc +1 more source
Retropubic versus transobturator slings: Medium‐term satisfaction and overactive bladder outcomes
Abstract Objective This study compares medium‐term outcomes of retropubic tension‐free vaginal tape (TVT) and transobturator tape (TOT) for stress urinary incontinence (SUI), focusing on patient satisfaction and overactive bladder (OAB) symptoms. Methods This prospective, single‐surgeon cohort study included women with SUI who underwent TVT or TOT at a
Erika Gandelsman +5 more
wiley +1 more source
Comparison of elastography score and strain ratio values according to the presence of stress urinary incontinence in transperineal elastography. [PDF]
Ata C +7 more
europepmc +1 more source
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi +35 more
wiley +1 more source
An unusual intraoperative finding during tension-free vaginal tape surgery for stress urinary incontinence: a case report. [PDF]
Posada MLC, Arias K.
europepmc +1 more source
Body Image Following Ostomy Surgery for Cancer: A Systematic Review
ABSTRACT Background Ostomy surgery, often required in the treatment of colorectal, bladder, prostate and gynaecological cancers, has profound effects on body image and psychosocial well‐being. While previous reviews have examined body image in colorectal cancer patients, no synthesis to date, to our knowledge, has focused on body image across cancer ...
Emma Hanlon +3 more
wiley +1 more source
Construction and Validation of a Nomogram for Diagnosis of Female Stress Urinary Incontinence Combined with Anatomic/Intrinsic Urethral Sphincter Deficiency. [PDF]
Hu G +5 more
europepmc +1 more source
The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo +11 more
wiley +1 more source
Innovations in Stress Urinary Incontinence: A Narrative Review. [PDF]
Szabo T +9 more
europepmc +1 more source

