Results 1 to 10 of about 3,069 (170)

Parasympathetic overdrive as a cause of overactive bladder in a high-fat-diet-induced obesity mouse model. [PDF]

J Physiol
Abstract figure legend Obesity and metabolic syndrome (MetS) are well‐known major risk factors for overactive bladder (OAB). Mechanisms underlying obesity‐/MetS‐associated OAB were explored using a high‐fat‐diet (HFD)‐induced obesity mouse model. HFD‐induced obesity/MetS mice developed an OAB phenotype characterized by enlarged non‐voiding contractions
Sugiura A, Mitsui R, Miwa-Nishimura K, Hashitani H.   +3 more
europepmc   +2 more sources

Animal Models of Hunner-Type Interstitial Cystitis. [PDF]

Int J Urol
ABSTRACT Background Animal models are crucial for mechanistic studies and therapeutic development of human diseases. At present, the etiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic disease of the urinary bladder, remains undefined.
Akiyama Y, Luo Y.
europepmc   +2 more sources

PCB Exposure in Adult Male Mice Reduces Proliferating Cells in the Prostate but Minimally Alters Voiding [PDF]

Toxics
Lower urinary tract dysfunction (LUTD) is a multifactorial disease process that encompasses diverse symptoms ranging from issues with storage and sensation to impaired emptying of the bladder.
Kathy Wang, Audrey Spiegelhoff, Tamryn Jordan, Thomas Lavery, Conner L. Kennedy, Monica M. Ridlon, Kimberly P. Keil Stietz   +6 more
doaj   +2 more sources

Odor-specific olfactory stimulation is associated with selective transcriptional changes and partial improvement of stress-evoked bladder overactivity in mice [PDF]

Frontiers in Neuroscience
Chronic psychological stress is known to induce functional and molecular alterations in central circuits regulating micturition. Here, we investigated whether odor-specific olfactory stimulation modulates stress-associated bladder dysfunction and related
Saori Nishijima, Katsumi Kadekawa, Katsuhiro Ashitomi, Je Tae Woo, Hiroaki Kitano, Kimio Sugaya   +5 more
doaj   +2 more sources

Is CO 2 cystometry a reliable test in estimating detrusor contractile function in patients with acute urinary retention?

Urological Science, 2017
Objectives: CO2 cystometry is very convenient for patients who already received indwelling urethral catheterization. This study aims to evaluate the reliability of CO2 cystometry in estimating the detrusor contractile function in patients with acute ...
Alex Tong-Long Lin, Kuang-Kuo Chen
exaly   +3 more sources

Automated Evaluation of Urodynamic Examinations Through Local Linear Models: Validation on Spinal Cord Injury Individuals [PDF]

IEEE Journal of Translational Engineering in Health and Medicine
Objective: Investigating consistent methods and metrics for classifying Detrusor Overactivity (DO) events and developing an automated robust method for clinical measurements calculation from cystometry data in persons with spinal cord injury (SCI ...
Wensi Zhang, Jurgen Pannek, Jens Wollner, Robert Riener, Diego Paez-Granados   +4 more
doaj   +2 more sources

Taking a Stand: A Prospective Study on the Influence of Posture on Urodynamic Studies in Older Patients [PDF]

Medicina
Background and Objectives: Urinary incontinence (UI) is a prevalent issue among older adults and may require urodynamic studies (UDSs) for accurate diagnosis.
Andries Van Huele, George Bou Kheir, Alan Wein, Veerle Decalf, Thomas F. Monaghan, François Hervé, Karel Everaert   +6 more
doaj   +2 more sources

Postoperative Reduction in Postvoid Residual Urine Volume May Be Associated With Bladder Capacity Decrease Rather Than an Increase in Tidal Voided Urine Volume in Patients With Pelvic Organ Prolapse. [PDF]

J Obstet Gynaecol Res
ABSTRACT Aim More than half of patients with pelvic organ prolapse (POP) complain of lower urinary tract symptoms (LUTS), especially voiding difficulty. Surgical approaches such as laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery (TVM) often result in improved voiding function in POP cases.
Kuroda K, Miyoshi H, Hamamoto K, Kawamura K, Masunaga A, Kobayashi H, Ito K.   +6 more
europepmc   +2 more sources

FIGO expert opinion management of post-obstetric fistula repair incontinence for vesicovaginal fistula. [PDF]

Int J Gynaecol Obstet
Abstract Post‐obstetric fistula repair incontinence (POFRI) is not unusual in fistula patients, and the diagnosis, as well as ongoing management of POFRI, can be challenging for surgeons, care teams, and patients alike. To address this issue and to start establishing consensus, FIGO (the International Federation of Gynecology & Obstetrics) held an ...
Goh J, Browning A, Slinger G, Trautvetter L.   +3 more
europepmc   +2 more sources

Detrusor Overactivity and Urodynamics. [PDF]

Neurourol Urodyn
ABSTRACT While overactive bladder (OAB) is a clinical diagnosis, detrusor overactivity is identified through urodynamic testing. UDS is usually considered when primary treatment for OAB fails, because UDS is expensive, time consuming, invasive, and sometimes inaccurate, and it is not considered to influence treatment strategy substantially.
Nguyen LN, Nadeau G.
europepmc   +2 more sources