Results 11 to 20 of about 3,069 (170)

Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]

open access: yesInternational Neurourology Journal, 2020
Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
doaj   +1 more source

Effects of electroacupuncture on bladder dysfunction and the expression of PACAP38 in a diabetic rat model

open access: yesFrontiers in Physiology, 2023
Objective: To explore the effects and the possible mechanism of electroacupuncture (EA) on diabetic bladder dysfunction (DBD) in streptozotocin-high fat diet (STZ-HFD) induced type 2 diabetes mellitus (T2DM) rats.Methods: The experiment was divided into ...
Xuke Han   +10 more
doaj   +1 more source

Assessing Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury: Animal Models in Preclinical Neuro-Urology Research

open access: yesBiomedicines, 2023
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding function and remains one of the leading causes of morbidity after spinal cord injury (SCI).
Adam W. Doelman   +4 more
doaj   +1 more source

The effect of posture and repetition on urodynamic parameters: A prospective randomized study [PDF]

open access: yesInvestigative and Clinical Urology, 2017
Purpose: To evaluate the effect of posture and repetition of filling cystometry on urodynamic parameters. Materials and Methods: Seventy-one men with benign prostatic hyperplasia participated in a urodynamic study between September 2015 and August 2016
Ho Joon Jeon   +2 more
doaj   +1 more source

The Role of Intra-abdominal Pressure Measurement in Awake Rat Cystometry [PDF]

open access: yesInternational Neurourology Journal, 2013
Rat cystometry is increasingly being used in research on overactive bladder and is a research tool for investigating bladder functions during the storage and voiding phases.
Tack Lee, Sang-Min Yoon
doaj   +1 more source

Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice

open access: yesAntioxidants, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory disease without consistently effective treatment. Among the many mediators implicated in cystitis, the overproduction of reactive oxygen species (ROS) seems to play a key role,
Mariana G. de Oliveira   +9 more
doaj   +1 more source

Machine learning-assisted fluoroscopy of bladder function in awake mice

open access: yeseLife, 2022
Understanding the lower urinary tract (LUT) and development of highly needed novel therapies to treat LUT disorders depends on accurate techniques to monitor LUT (dys)function in preclinical models. We recently developed videocystometry in rodents, which
Helene De Bruyn   +4 more
doaj   +1 more source

The Aged Lower Urinary Tract: Deficits in Neural Control Mechanisms

open access: yesFrontiers in Aging, 2021
Bothersome urinary symptoms plague many older adults and disproportionally affect women. Underreporting of symptoms and general stigma/embarrassment associated with incontinence has negatively impacted the availability of treatments, as research cannot ...
Cara C. Hardy   +2 more
doaj   +1 more source

Ventrolateral Periaqueductal Gray Neurons Are Active During Urination

open access: yesFrontiers in Cellular Neuroscience, 2022
The ventrolateral periaqueductal gray (VLPAG) is thought to be the main PAG column for bladder control. PAG neurons (especially VLPAG neurons) and neurons in the pontine micturition center (PMC) innervating the bladder detrusor have anatomical and ...
Yu Rao   +13 more
doaj   +1 more source

TRPA1 channel mediates methylglyoxal-induced mouse bladder dysfunction

open access: yesFrontiers in Physiology, 2023
Introduction: The transient receptor potential ankyrin 1 channel (TRPA1) is expressed in urothelial cells and bladder nerve endings. Hyperglycemia in diabetic individuals induces accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO),
Akila L. Oliveira   +6 more
doaj   +1 more source

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