Results 41 to 50 of about 3,069 (170)
ABSTRACT Introduction Overactive bladder (OAB) is defined as urinary urgency, usually accompanied by increased daytime frequency and/or nocturia, with urgency urinary incontinence (OAB‐wet) or without (OAB‐dry), in the absence of urinary tract infection or other detectable disease.
John E. Speich +9 more
wiley +1 more source
ABSTRACT Introduction Maintenance of bladder filling and urinary storage at low intravesical pressures is fundamental to minimizing risk to the upper urinary tract. Bladder compliance describes the relationship between the bladder volume and the change in detrusor pressure during the filling phase of urodynamics.
Eric Rovner +5 more
wiley +1 more source
Impact of deep resection of endometriosis in the pelvis on urodynamic parameters
Purpose: To evaluate the effects of deep resection of endometriosis in the posterior pelvic region on urodynamic parameters. Methods: A prospective observational study conducted with female patients diagnosed with deep pelvic endometriosis before and ...
Jardel Cavalcante de Farias +4 more
doaj +1 more source
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan +3 more
wiley +1 more source
Measurement of Urinary Bladder Pressure: A Comparison of Methods
Pressure is an essential parameter for the normal function of almost all organs in the human body. Measurement of pressure is therefore highly important in clinical practice and medical research.
Ingelin Clausen +2 more
doaj +1 more source
ABSTRACT Purpose There are few reports investigating urodynamic changes after radiotherapy and hormonal therapy (HT) for prostate cancer. We prospectively evaluated differences in bladder outlet obstruction (BOO) using pressure‐flow studies (PFS) before and after HT and radiotherapy in patients with high‐risk localized or locally advanced prostate ...
Yuki Kyoda +7 more
wiley +1 more source
Seventy‐Five Years of NIH NIDDK Funding Has Increased Knowledge and Greatly Impacted Clinical Care
ABSTRACT Seventy‐five years of research funding in benign Urology from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health has greatly advanced not only our knowledge of etiology and mechanisms of nononcologic urological conditions but has also advanced new technologies and treatments to ...
Ana G. Hernandez‐Reynoso +3 more
wiley +1 more source
ABSTRACT Aim Autonomic nervous system (ANS) imbalance may contribute to functional pelvic disorders such as overactive bladder (OAB). Transcutaneous tibial nerve stimulation (TTNS) is a non‐invasive therapy for OAB; however, its autonomic modulation mechanisms remain unclear. This exploratory study evaluated the acute effects of TTNS on ANS activity in
Javier A. Muñoz +9 more
wiley +1 more source
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang +10 more
wiley +1 more source
Mirodenafil Prevents Bladder Dysfunction Induced by Chronic Bladder Ischemia in Rats [PDF]
Purpose: To investigate the protective effect of mirodenafil on bladder function in a rat model of chronic bladder ischemia (CBI). Methods: Twenty-four Sprague-Dawley rats were randomized to three groups: untreated, sham-operated rats (control group ...
Hoon Choi +5 more
doaj +1 more source

