Void spot assay visualization optimization for use of Void Whizzard in rats (Rattus norvegicus) [PDF]
Physiological ReportsVoid spot assay (VSA) noninvasively evaluates urination. This study optimizes VSA by comparing post‐assay paper visualization techniques: bright field light (BF), ultraviolet light (UV), and ninhydrin spray (N).
Hannah Ruetten +4 more
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A “NEW” way to look at an “old” test: Transforming the void spot assay (VSA) into a diagnostic tool [PDF]
Physiological Reports, 2021 Marianela G. Dalghi
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PCB Exposure in Adult Male Mice Reduces Proliferating Cells in the Prostate but Minimally Alters Voiding [PDF]
ToxicsLower urinary tract dysfunction (LUTD) is a multifactorial disease process that encompasses diverse symptoms ranging from issues with storage and sensation to impaired emptying of the bladder.
Kathy Wang +6 more
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Piezo2 in sensory neurons contributes to inflammation-induced bladder overactivity and is associated with the effects of electroacupuncture [PDF]
Frontiers in NeuroscienceObjectivesTo assess the effects of varying doses of cyclophosphamide (CYP) on lower urinary tract function in rats, and to further investigate the role of Piezo2 in sensory neurons in a CYP-induced interstitial cystitis/bladder pain syndrome (IC/BPS ...
Xu Li +11 more
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Conditional deletion of Tmem63b does not impact mouse voiding behavior. [PDF]
PLoS ONEThe proper function of the lower urinary tract depends on its ability to sense and react to mechanical forces as urine is produced, transported, stored, and eliminated; however, our current understanding of the mechanosensors involved in these events is ...
Marianela G Dalghi +6 more
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ML‐UrineQuant: A machine learning program for identifying and quantifying mouse urine on absorbent paper [PDF]
Physiological ReportsThe void spot assay has gained popularity as a way of assessing functional bladder voiding parameters in mice, but analyzing the size and distribution of urine spot patterns on filter paper with software remains problematic due to inter‐laboratory ...
Warren G. Hill +5 more
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The RAGE Inhibitor TTP488 (Azeliragon) Improves Diabetic Bladder Dysfunction in Leptin-Deficient Obese Mice [PDF]
AntioxidantsThe advanced glycation end product (AGE)–RAGE axis has been implicated in the pathophysiology of diabetic bladder dysfunction (DBD). However, no previous studies have explored the effects of RAGE blockade on this condition.
Akila Lara Oliveira +5 more
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Sex differences in peripheral and local immune responses following spinal cord injury [PDF]
Frontiers in ImmunologyIntroductionBiological sex has been shown to influence immune function and inflammatory responses. However, most preclinical studies in spinal cord injury (SCI) have predominantly used female animals, potentially introducing a sex bias in our ...
Sara Rito-Fernandes +31 more
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An innovative electrical neurostimulation approach to mimic reflexive urination control in spinal cord injury models [PDF]
Scientific ReportsNeurogenic lower urinary tract dysfunction (NLUTD) is a frequent consequence of spinal cord injury (SCI), leading to symptoms that significantly impact quality of life.
Jun Li +8 more
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Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice [PDF]
Neurourology and Urodynamics, 2016 Chad Vezina, William A Ricke, Lingjun Li
exaly +2 more sources