Results 11 to 20 of about 1,207,771 (210)

Void spot assay procedural optimization and software for rapid and objective quantification of rodent voiding function, including overlapping urine spots

American Journal of Physiology - Renal Physiology, 2018
Mouse urinary behavior is quantifiable and is used to pinpoint mechanisms of voiding dysfunction and evaluate potential human therapies. Approaches to evaluate mouse urinary function vary widely among laboratories, however, complicating cross-study ...
Chad Vezina, Jill Macoska, Kevin Eliceiri   +2 more
exaly   +3 more sources

Void spot assay: recommendations on the use of a simple micturition assay for mice

American Journal of Physiology - Renal Physiology, 2018
Chad Vezina, Warren G. Hill
exaly   +2 more sources

Monitoring Gas Void Fraction In Two-Phase Flow With Acoustic Emission [PDF]

, 2010
The two-phase gas/liquid flow phenomenon can be encountered over a range of gas and liquid flow rates in the chemical engineering industry, particularly in oil and gas production transportation pipelines.
Addali, Abdulmajid
core   +7 more sources

Spoti-find: a novel, open-source void spot assay image analysis tool. [PDF]

American Journal of Physiology - Renal Physiology
Ron Korstanje, William A Ricke, Seamus Mawe   +2 more
exaly   +2 more sources

Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice

Antioxidants, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory disease without consistently effective treatment. Among the many mediators implicated in cystitis, the overproduction of reactive oxygen species (ROS) seems to play a key role,
Mariana G. de Oliveira, Fabíola Z. Monica, Gabriela R. Passos, Jamaira A. Victorio, Ana Paula Davel, Anna Lethicia Lima Oliveira, Carlos A. Parada, Carlos A. L. D’Ancona, Warren G. Hill, Edson Antunes   +9 more
doaj   +1 more source

Anti-fibrotic effect of tocotrienols for bladder dysfunction due to partial bladder outlet obstruction [PDF]

Investigative and Clinical Urology, 2023
Purpose: To investigate potential beneficial effects of tocotrienols which have been suggested to inhibit hypoxia-inducible factor (HIF) pathway, on partial bladder outlet obstruction (PBOO)-induced bladder pathology.
Nao Iguchi, M. İrfan Dönmez , Anna P. Malykhina, Duncan T. Wilcox   +3 more
doaj   +1 more source

TRPA1 channel mediates methylglyoxal-induced mouse bladder dysfunction

Frontiers in Physiology, 2023
Introduction: The transient receptor potential ankyrin 1 channel (TRPA1) is expressed in urothelial cells and bladder nerve endings. Hyperglycemia in diabetic individuals induces accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO),
Akila L. Oliveira, Matheus L. Medeiros, Erick de Toledo Gomes, Glaucia Coelho Mello, Soraia Katia Pereira Costa, Fabíola Z. Mónica, Edson Antunes   +6 more
doaj   +1 more source

A Spectrum of Age- and Gender-Dependent Lower Urinary Tract Phenotypes in Three Mouse Models of Type 2 Diabetes

Metabolites, 2023
Lower urinary tract symptoms are extremely common in people with diabetes and obesity, but the causes are unclear. Furthermore, it has proven difficult to reliably demonstrate bladder dysfunction in diabetic mouse models, thus limiting the ability to ...
Bryce MacIver, Erica M. Bien, Mariana G. de Oliveira, Warren G. Hill   +3 more
doaj   +1 more source

A NEW approach for characterizing mouse urinary pathophysiologies

Physiological Reports, 2021
The void spot assay (VSA) is a cost‐effective method for evaluating and quantifying mouse urinary voiding phenotypes. The VSA has been used to differentiate voiding behaviors between experimental groups, but not as a diagnostic assay.
Hannah M. Ruetten, Gervaise H. Henry, Teresa T. Liu, Heidi M. Spratt, William A. Ricke, Douglas W. Strand, Chad M. Vezina   +6 more
doaj   +1 more source

Adaptation of the Ultrasensitive HIV-1 p24 Antigen Assay to Dried Blood Spot Testing. [PDF]

, 2007
Implementation of molecular tests for the assessment of pediatric HIV-1 infection in resource-limited countries is difficult because of technical complexity and costs.
Speck, R F, Böni, J, Jullu, B, Schüpbach, J, Knuchel, M C, Mshinda, H, Schüpbach, Jörg, Nadal, D, Stoeckle, Marcel P, Tanner, M, Böni, Jürg, Shah, Cyril, Jullu, Boniphace, Speck, Roberto F, Shah, C, Tomasik, Z, Stoeckle, M P, Nadal, David, Tomasik, Zuzana, Mshinda, Hassan, Knuchel, Marlyse C, Tanner, Marcel   +21 more
core   +1 more source