Results 101 to 110 of about 1,522,607 (355)

Status stres psikososial dan hubungannya dengan status gizi siswa SMP Stella Duce 1 Yogyakarta

open access: yesJurnal Gizi Klinik Indonesia, 2010
Background: Adolescent is a transition phase from childhood to adulthood that marked by the change on physical, mental and psychosocial aspect. Adaptation on the change that people met in their life is called psychosocial stress. Stress makes a change on
Mutiara Tirta Prabandari Lintang Kusuma   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Impact of Situational Constraints, Role Stressors, and Commitment on Employee Altruism [PDF]

open access: yes, 2003
This study investigated relations between 3 work-related stressors (role ambiguity, role conflict, and organizational constraints) and altruistic behavior in the workplace.
Adams, Gary A.   +3 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Morphing surfaces for the control of boundary layer transition [PDF]

open access: yes, 2016
A structure configured to modify its surface morphology between a smooth state and a rough state in response to an applied stress. In demonstrated examples, a soft (PDMS) substrate is produced, and is pre-strained. A relatively stiff overlayer of a metal,
Bhattacharya, Kaushik   +2 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Pengaruh Tekanan Pekerjaan dan Stres Pekerjaan terhadap Evaluasi Kinerja

open access: yesJournal the Winners, 2009
The lawyer profession at this time has become the public spotlight due to their role in upholding justice and defending the oppressed. This noble work requires reliable performance.
Jerry M. Logahan
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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