Results 121 to 130 of about 1,522,607 (355)

GAMBARAN STRESSOR PADA LANSIA YANG TINGGAL DI RUMAH BERSAMA KELUARGA DAN DI UPTD (UNIT PELAKSANA TEKNIS DINAS) RUMOH SEUJAHTERA GEUNASEH SAYANG BANDA ACEH TAHUN 2012 [PDF]

, 2012
KEMENTRIAN PENDIDIKAN NASIONALUNIVERSITAS SYIAH KUALAFAKULTAS KEDOKTERAN PROGRAM STUDI ILMU KEPERAWATAN SKRIPSI19 Oktober 2012xv Halaman + VI Bab + 100 Halaman + 17 Tabel + 1 Skema + 19 Lampiran ZUHAIRA FNIM.
ZUHAIRA F
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

THE STRESS STATE OF A RECTANGULAR CROSS SECTION BEAM MADE OF A MATERIAL WITH POROUS STRUCTURE AT PURE BENDING [PDF]

, 2017
Danila Yur’evich GAVRILOV
openalex   +1 more source

Driver-pressure-impact and response-recovery chains in European rivers: observed and predicted effects on BQEs [PDF]

, 2011
The report presented in the following is part of the outcome of WISER’s river Workpackage WP5.1 and as such part of the module on aquatic ecosystem management and restoration. The ultimate goal of WP5.1 is to provide guidance on best practice restoration
Dahm, V., Feld, C.K., Keizer-Vlek, H.E., Logez, M., Lorenz, A., Marzin, A., Michels, H.C.U., Verdonschot, P.F.M.   +7 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Job Stressors from Clinical Nurses’ Perspective

نشریه پرستاری ایران, 2011
Background & Aim: Nursing by its very nature is subject to high degrees of stress and is very important because of its relation with human’s life.
Torshizi L. MSc, Ahmadi F. PhD
doaj  

stressor

Citation: 'stressor' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15066 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

A Transverse Examination of Occupational Stress Among a Cross Disciplinary Population of Irish Construction Professionals

, 2020
Myles Keaveney
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source