Results 171 to 180 of about 1,514,931 (310)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Stressor marrow response in the case of neonatal sepsis – Significance of nRBCs in peripheral smears [PDF]

open access: yesMedical Laboratory Journal
Background: Nucleated red blood cells (nRBCs) are immature erythrocytes whose production is thought to be driven primarily by the interplay of hypoxia and erythropoietin synthesis.
Neema Tiwari   +2 more
doaj  

Sensing stress responses in potato with whole-plant redox imaging

open access: green, 2021
Matanel Hipsch   +5 more
openalex   +2 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Neutron diffraction measurements of residual stress in additively manufactured stainless steel

open access: green, 2016
Donald W. Brown   +5 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

CRESTA: a comprehensive transcriptome atlas for cellular response to external stressors. [PDF]

open access: yesNucleic Acids Res
Wang H   +13 more
europepmc   +1 more source

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