Results 81 to 90 of about 5,188,883 (353)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Stress, person, personality. From distress to eustress

Studia Humanitatis, 2020
This article analyses problems of human response to stressors and ways to overcome distress. The article pays special attention to the psychological aspect of stress as an adaptive response to various types of stimuli.
Staniszewska Żanna
doaj  

Mild acute stress improves response speed without impairing accuracy or interference control in two selective attention tasks: Implications for theories of stress and cognition. [PDF]

, 2019
Acute stress is generally thought to impair performance on tasks thought to rely on selective attention. This effect has been well established for moderate to severe stressors, but no study has examined how a mild stressor-the most common type of ...
Ramey, Michelle M, Rivers, Andrew M, Shields, Grant S, Trainor, Brian C, Yonelinas, Andrew P   +4 more
core  

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Risk of childhood asthma following prenatal exposure to negative life events and job stressors: A nationwide register-based study in Denmark

Scandinavian Journal of Work, Environment & Health, 2019
OBJECTIVES: This study aimed to examine the association between negative life events, job stressors (low job control or high psychosocial job demands) and offspring asthma phenotypes (early-onset transient, early-onset persistent and late-onset asthma ...
Xiaoqin Liu, Kathrine Pape Madsen, Camilla Sandal Sejbaek, Henrik A Kolstad, Jens Peter Ellekilde Bonde, Jørn Olsen, Karin Sørig Hougaard, Kirsten Skamstrup Hansen, Niklas Worm Andersson, Reiner Rugulies, Vivi Schlünssen   +10 more
doaj   +1 more source

Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity. [PDF]

, 2016
Severe, repeated or chronic stress produces negative health outcomes including disruptions of the sleep/wake cycle and gut microbial dysbiosis. Diets rich in prebiotics and glycoproteins impact the gut microbiota and may increase gut microbial species ...
Berg, Brian M, Chichlowski, Maciej, Fleshner, Monika, Greenwood, Benjamin N, Knight, Rob, Mika, Agnieszka, Roller, Rachel, Thompson, Robert S   +7 more
core   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

SNIFFER WFD119: Enhancement of the River Invertebrate Classification Tool (RICT) [PDF]

, 2011
EXECUTIVE SUMMARY Project funders/partners: Environment Agency (EA), Northern Ireland Environment Agency (NIEA), Scotland & Northern Ireland Forum for Environmental Research (SNIFFER), Scottish Environment Protection Agency (SEPA) Background to ...
Clarke, Ralph T., Davy-Bowker, John, Dunbar, M., Laize, C., Murphy, J.F., Scarlett, P.M.   +5 more
core  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

A Brain Phenotype for Stressor‐Evoked Blood Pressure Reactivity

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Individuals who exhibit large‐magnitude blood pressure (BP) reactions to acute psychological stressors are at risk for hypertension and premature death by cardiovascular disease.
P. Gianaros, L. Sheu, Fatma Uyar, Jayanth Koushik, J. Jennings, T. Wager, Aarti Singh, T. Verstynen   +7 more
semanticscholar   +1 more source