Results 91 to 100 of about 789,824 (307)

Predicting occupational strain and job satisfaction: the role of stress, coping, personality, and affectivity variables [PDF]

, 1999
Four studies employed path analysis to examine how measures of occupational stressors, coping resources, and negative affectivity (NA) and positive affectivity (PA) interact to predict occupational strain.
Gabrielle I. Lalor, Gerard J. Fogarty, Lynette F. Sutherl, M. Anthony Machin, Majella J. Albion, Predicting Occupational Strain, Susan Revitt   +6 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Socio-demographic Characteristics, Clinical Variables, the Role of Stressor and Phenomenology in Patients with Acute and Transient Psychotic Disorders in One of the Tertiary Care Centre of North India: A Cross-sectional Study

Journal of the Scientific Society
Background: Acute and transient psychotic disorders (ATPDs) have benign course and takes place in the existence of noticeable and exceptionally traumatic stressors (direct temporal association between stressors and occurrence of ATPD) which necessitate ...
Mahender Singh, Dinesh Dutt Sharma, Sunny Garg, Devesh Sharma, Alka Chauhan   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Demographic variables, clinical aspects, and medicolegal implications in a population of patients with adjustment disorder [PDF]

, 2016
INTRODUCTION: Although adjustment disorder (AD) is considered as residual diagnosis and receives little attention in research, it plays an important role in clinical practice and also assumes an increasingly important role in the field of legal medicine,
Anastasia, Annalisa, Bersani, Giuseppe, Colletti, Chiara, Cuoco, Valentina, Quartini, Adele, Rinaldi, Raffaella, Urso, Stefania   +6 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The multitasking framework: the effects of increasing workload on acute psychobiological stress reactivity [PDF]

, 2013
A variety of techniques exist for eliciting acute psychological stress in the laboratory; however, they vary in terms of their ease of use, reliability to elicit consistent responses and the extent to which they represent the stressors encountered in ...
Carter, Kirsty, Wetherell, Mark
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Impact of Stressors/Stress on Organizational Commitment of Engineers in the Construction Industry

Buildings
Engineers often play vital roles in technical planning, designing, and operating projects, as well as implementing standard requirements in the physical sites.
Mei-Yung Leung, Khursheed Ahmed, Isabella Y. S. Chan   +2 more
doaj   +1 more source