Results 151 to 160 of about 4,828,283 (358)

Co-RESPOND: a federated network of cohorts on mental health and adversity during the COVID-19 pandemic. Challenges, solutions and recommendations for retrospective data harmonization

open access: yesEuropean Journal of Psychotraumatology
Background: The SARS-Cov-2 pandemic was associated with a substantial rise in trauma and stressor exposure. The Co-RESPOND consortium (part of the EU horizon 2020-funded RESPOND project) has been initiated to study the impact on mental health, using ...
Papoula Petri-Romão   +24 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development of role stressors model towards burnout: empirical study from Indonesia [PDF]

open access: yes, 2016
Burnout is physical, emotional and mental exhaustion resulting from chronic emotional burden.One antecedent factor of burnout is role stressor.The dimensions of role stressors are role conflict, role ambiguity, and role overload.These dimensions are ...
Lina, Lina
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Challenge stressors: longitudinal effects on self attitudes, work attitudes, and health. [PDF]

open access: yes, 2014
Recent research suggests that some stressors (i.e. hindrance stressors) have mainly negative consequences, whereas others (i.e. challenge stressors) can simultaneously have positive and negative consequences (e.g., LePine et al., 2005). Although a number
Widmer, Pascale   +3 more
core  

Clinical Education Stressors from the Perspective of Students of Nursing, Midwifery, and Operating Room: A Study in Kurdistan University of Medical Sciences [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Continuous investigation of educational stressors, and managing them is essential for quality improvement of clinical education. This study investigated stressors of clinical education from the perspective of nursing, midwifery and ...
golrokh moridi   +6 more
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Greater Work-Related Stress Among Chinese Media Workers in the Context of Media Transformation: Specific Stressors and Coping Strategies

open access: yesInternational Journal of Communication, 2016
A steady rise in unexpected deaths of Chinese media workers from 2011 to 2015 highlights a new social problem. Content analysis of official reports about these deaths reveals the contribution of work-related stress and media transformation.
Min Wang, Zuosu Jiang
doaj  

Gender Analysis of Stress and Smoking Behavior: A Survey of Young Adults in Japan

open access: yesSocial Sciences
The global tobacco epidemic, claiming over 8 million lives annually, constitutes a formidable public health threat. Fatalities arise from both direct tobacco use and exposure to second-hand smoke.
Ayuka Yokoyama   +3 more
doaj   +1 more source

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