Results 171 to 180 of about 489,418 (300)

Exploring Psychosocial Stressors, Exam Performance, and Grit Among Preclinical Medical Students. [PDF]

Adv Med Educ Pract
Iwuagwu RJ, Clark MF, Landoll RR, Jonas C, Thornton K, Torre D, Durning SJ.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Multidimensional workplace stressors differentially impact cognitive trajectories. [PDF]

Alzheimers Dement
Walters ME, Scambray KA, Palms JD, Pierce RM, Sol K, Zahodne LB.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Independent trajectories of cognitive function and daily events across 9 years during midlife and old age. [PDF]

J Gerontol B Psychol Sci Soc Sci
Klaiber P, Almeida DM, Ballhausen N.
europepmc   +1 more source

Stressors and Cardiovascular Disease

Heart and Mind, 2022
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Job stressors and incident lipid-lowering medications in the working population: prospective results from the national French ESPS survey. [PDF]

Eur J Public Health
Niedhammer I, Quatrevaux M.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Discrete components of stress impact trajectories of childhood irritability but not adolescent mental health outcomes. [PDF]

JCPP Adv
DeSerisy M, Yang H, Cohen JW, Pagliaccio D, Herbstman JB, Peterson BS, Perera FP, Rauh V, Margolis AE.   +8 more
europepmc   +1 more source