Results 91 to 100 of about 5,378,814 (297)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Rate-dependent domain spacing in a stretched NiTi strip
International Journal of Solids and Structures, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
He, Y.J., Sun, Q.P.
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Effects of Mechanical Stretch on Collagen and Cross-Linking in Engineered Blood Vessels
Cell Transplantation, 2009 It has been shown that mechanical stimulation affects the physical properties of multiple types of engineered tissues. However, the optimum regimen for applying cyclic radial stretch to engineered arteries is not well understood.
Amy Solan +2 more
doaj +1 more source
Cardiac myosin binding protein-C phosphorylation modulates myofilament length-dependent activation
Frontiers in Physiology, 2016 Cardiac myosin binding protein-C (cMyBP-C) phosphorylation is an important regulator of contractile function, however, its contributions to length-dependent (SL) changes in cross-bridge (XB) kinetics is unknown.
Ranganath eMamidi +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Effects of Microalloying on Stretch-flangeability of Ultrahigh-strength TRIP-aided Martensitic Steel Sheets [PDF]
, 2014 The effects of Cr, Mo, and Ni addition on the microstructure and stretch-flangeability of a 0.2%C-1.5%Si-1.5%Mn-0.05%Nb (mass%) transformation-induced plasticity (TRIP)-aided martensitic steel sheet produced by an isothermal transformation process at a ...
Sugimoto, Koh-ichi +2 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2019 Theresa Stretch is a native of the State of Illinois. After working as a food service director in both rural and metropolitan districts in Illinois, Theresa accepted a position as an Education and Training Specialist at the Institute of Child Nutrition ...
Institute of Child Nutrition. Child Nutrition Archives. +1 more
core +1 more source
Intrafusal cross‐bridge dynamics shape history‐dependent muscle spindle responses to stretch
Experimental PhysiologyComputational models can be critical to linking complex properties of muscle spindle organs to the sensory information that they encode during behaviours such as postural sway and locomotion where few muscle spindle recordings exist.
Surabhi N. Simha, Lena H. Ting
doaj +1 more source