Results 101 to 110 of about 13,470,362 (342)

The Exponentially Faster Stick-Slip Dynamics of the Peeling of an Adhesive Tape

open access: yes, 2014
The stick-slip dynamics is considered from the nonlinear differential-algebraic equation (DAE) point of view and the peeling dynamics is shown to be a switching differential index DAE model.
Mishra, Nachiketa   +2 more
core   +1 more source

Femtosecond real-time probing of reactions. XI. The elementary OClO fragmentation [PDF]

open access: yes, 1993
Femtosecond reaction dynamics of OClO in a supersonic molecular beam are reported. The system is excited to the A 2A2 state with a femtosecond pulse, covering a range of excitation in the symmetric stretch between v1=17 to v1=11 (308–352 nm).
Baumert, T., Herek, J. L., Zewail, A. H.
core   +1 more source

Hot stretch forming of titanium sheet by resistance heating

open access: yesMATEC Web of Conferences, 2018
Titanium alloys are important aerospace materials due to excellent comprehensive performance, but it is difficult to form at room temperature. Electrically assisted hot stretch forming is used to form the titanium panels of aircraft.
Li Xiaoqiang   +3 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Single cell mechanics: stress stiffening and kinematic hardening

open access: yes, 2007
Cell mechanical properties are fundamental to the organism but remain poorly understood. We report a comprehensive phenomenological framework for the nonlinear rheology of single fibroblast cells: a superposition of elastic stiffening and viscoplastic ...
A. Mogilner   +10 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Progressive damage and rupture in polymers

open access: yes, 2017
Progressive damage, which eventually leads to failure, is ubiquitous in biological and synthetic polymers. The simplest case to consider is that of elastomeric materials, which can undergo large reversible deformations with negligible rate dependence. In
Anand, Lallit   +2 more
core   +1 more source

Centrifugal stretching effect to intra-band E2-transition rates

open access: yesPhysics Letters B, 1971
Abstract The angular momentum projection method is applied to the calculation of the intra-band B(E2)-transition rates of even nuclei in the rare-earth region. It is shown that the centrifugal stretching model can reproduce the experimental results for the transitions in the higher spin states of the ground state rotational band with satisfying ...
T. Takemasa, M. Sano
openaire   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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