Results 61 to 70 of about 957,800 (297)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A numerical study of stretched smectic-A elastomer sheets
We present a numerical study of stretching monodomain smectic-A elastomer sheets, computed using the finite element method. When stretched parallel to the layer normal the microscopic layers in smectic elastomers are unstable to a transition to a buckled
Adams, James M., Brown, Andrew W.
core +1 more source
Effects of Additional Radial Shock Wave Therapy on Spasticity of Upper Extremity Muscle
Background: Spasticity is one of the most common problems and greatly interferes with the functional capacity of chronic stroke patients. The most commonly used treatments are infrared therapy and stretching exercises, but they have not reduced ...
Go Linda Sugiarto, Tanti Ajoe Kesoema
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Elastic moduli renormalization in self interacting stretchable polyelectrolytes
We study the effect of intersegment interactions on the effective bending and stretching moduli of a semiflexible polymer chain with a finite stretching modulus.
Hansen, Per Lyngs +2 more
core +1 more source
IntroductionInfrared thermography is gaining attention in the field of sports medicine and performance. This study investigated the effects of static and dynamic warm-ups and a 90° change of direction (COD) exercise on the thermal response of the knee ...
Bruno Trovato +6 more
doaj +1 more source
Sport-climbing popularity increased intensely over the past years. Particularly, children’s and adolescents’ interest therein is constantly growing. Despite a large effort in preventing injuries and muscle overloads, a fine-tuned training for
Ludovica Gasbarro +6 more
doaj +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Lattice stretching bistability and dynamic heterogeneity [PDF]
A simple one-dimensional lattice model is suggested to describe the experimentally observed plateau in force-stretching diagrams for some macromolecules.
Christiansen, P. L. +2 more
core +2 more sources

