Results 41 to 50 of about 5,097,379 (301)
Asian Journal of Pharmaceutical Sciences, 2019 Particle shape has been recognized as one of the key properties of nanoparticles in biomedical applications including targeted drug delivery. Targeting ability of shape-engineered particles depends largely on targeting ligands conjugated on the particle ...
Jiafu Cao +6 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Open PhysicsThis article presented micropolar hybrid nanofluid flow comprising copper and alumina nanoparticles over a flat sheet. The mixed convection phenomenon is studied under the effect of gravity.
Algehyne Ebrahem A. +3 more
doaj +1 more source
Convective heat transfer in a micropolar fluid over an unsteady stretching surface [PDF]
, 2016 An unsteady boundary layer free convective flow and heat transfer of a viscous incompressible, microploar fluid over a vertical stretching sheet is investigated. The stretching velocity is assumed to vary linearly with the distance along the sheet.
Prasad, K. V. +5 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Self-locking Kirigami surfaces via controlled stretching
Communications Engineering, 2023 Abstract Kirigami provides a powerful strategy to transform two-dimensional elements into complex three-dimensional functional structures with lengths ranging from nanoscale to microscale and macroscale. The stability and programmability of forming three-dimensional structures through mechanical actuation, whether external or self ...
Qian Zhang +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Nanomaterials, 2022 In this study, graphene quantum dots (GQDs) and polyvinyl alcohol (PVA) composite was prepared and then coated on the surface of gold thin film via the spin coating technique.
Nurul Illya Muhamad Fauzi +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source