Results 221 to 230 of about 192,251 (301)

Corynebacterium striatum [PDF]

, 2020
openaire   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Transient weakening of the blood-brain barrier in neonatal mice. [PDF]

Fluids Barriers CNS
Hanafy AS, Dietrich D.
europepmc   +1 more source

Happy me: Asymmetric bidirectional links between the self and positivity underpin biased processing

British Journal of Psychology, EarlyView.
Abstract Understanding how the self relates to emotional valence is fundamental to theories of self‐concept and cognitive bias. While separate literatures have documented advantages for information associated with the self and information of positive valence, the mechanisms and directionality of their interaction remain poorly understood.
Naomi A. Lee, Douglas Martin, Jie Sui
wiley   +1 more source

Distinct Transcriptomic Signatures of HIV-1 Tat and gp120 Uncover Differential Neuroimmune Vulnerability in a <i>Gba1</i>-Deficient Synucleinopathy Model. [PDF]

Curr Issues Mol Biol
Lagni A, Lotti V, Diani E, Cecchetto R, Turrina S, Raniero D, Palmisano A, Mazzariol A, Gibellini D, Paolone G.   +9 more
europepmc   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

NLX-112, a Selective 5-HT1A Receptor Agonist, Upregulates GDNF and is Neuroprotective Against MPTP-Induced Nigrostriatal Degeneration in a Mouse Model of Parkinson's Disease. [PDF]

ACS Chem Neurosci
Powell WH, Annett LE, Depoortere R, Newman-Tancredi A, Iravani MM.   +4 more
europepmc   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Sertraline and Escitalopram But Not Other Antidepressants Increase Acetylcholinesterase Activity <i>Ex Vivo</i> in the Rat Frontal Cortex. [PDF]

Ann Neurosci
Dharwadkar J, Nayak AR, Rao BSS, Srikumar BN.   +3 more
europepmc   +1 more source

Clinicopathological and molecular heterogeneity of amyloid‐β in unnatural deaths under 70 years: A forensic autopsy–based study

Brain Pathology, EarlyView.
This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata, Yukiko Hata, Koji Yoshida, Ryo Tanaka, Shigeo Murayama   +4 more
wiley   +1 more source