Results 101 to 110 of about 1,593 (170)

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Phylogenomics of Western Eurasian Tilia: merging GBS datasets to place the Hyrcanian forest limes. [PDF]

BMC Plant Biol
Ala N, Bagheri A, Zare H, Himmelbach A, Harpke D, Blattner FR.   +5 more
europepmc   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Optimization of femtosecond laser spot coverage: analytical modeling of spatial frequencies, anisotropy, and saturation boundaries. [PDF]

Biomed Opt Express
Mosquera SA.
europepmc   +1 more source

Engineering Strategies to Suppress Thermal Runaway Propagation in Lithium‐Ion Battery: Mechanisms, Metrics, Materials, and Evaluation Methods

Advanced Science, EarlyView.
Thermal runaway propagation can transform a single‐cell failure into a system‐level hazard in lithium‐ion battery packs. This review clarifies how heat transfer, gas venting, combustion, and configuration govern cell‐to‐cell failure, and links measurable metrics, pathway‐oriented suppression materials, and experimental/modeling tools to guide safer ...
Jinrong Su, Anna DiFelice, Jayani Mawela, Jianing Gan, Shuai Che, Wonhee Cho, Hanghang Yan, Yaohong Xiao, Xinxin Yao, Xiangwei Guo, Rui Wang, Dingchuan Xue, Hanlong Liu, Solomon Adera, Zhan Chen, Lei Chen   +15 more
wiley   +1 more source

The association between birthweight and adult lung function: insights from the UK Biobank. [PDF]

BMC Pulm Med
Wang Y, Zhang Y, Bo Y, Li P, Jiang T, Li Y, Cheng Z, Zhu Y.   +7 more
europepmc   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

Advanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Circulating cell-free mtDNA fragmentomics for early detection of gastric cancer and precancerous lesions. [PDF]

Cell Rep Med
Dang M, Wang S, Zhang H, Xu H, Lu L, Liu Y, Jiao H, Yang W, Peng F, Gao X, Lin F, Dong K, Pan K, Li W, Lu R, Nie Y, Liu Y, Xing J.   +17 more
europepmc   +1 more source

Wearable Electro‐Thermal Haptic Stimulator Driven by a Self‐Powered Tactile Sensor for Realistic Stimulus Replication

Advanced Science, EarlyView.
We present a stimulus‐replicating system combining a tactile sensor with a wearable Peltier thermotactile module and concentric electrotactile electrode. Signals encoding pressure and temperature drive the stimulators to reproduce mechano‐thermal cues on the skin. AlN/PDMS encapsulation and SA/LA PSA ensure mechanical compliance and thermal efficiency.
Ey‐In Lee, Chae‐Young Kang, Kyuhyun Hwang, Jongbaeg Kim, Jin‐Woo Park   +4 more
wiley   +1 more source

Phospholipid Nanoparticle Resuscitation Preserves Neuronal Integrity and Cognitive Recovery Without Exacerbating Neuroinflammation Following Hemorrhagic Shock-Induced Clinical Death. [PDF]

Biomedicines
Shallie P, Carpenter N, Sheikh Hussein O, Kumaresan H, Kinsey D, Shallie O, Daniel G, Rosario G, Moncure M, Simpkins CO.   +9 more
europepmc   +1 more source