Results 71 to 80 of about 77,845 (358)

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

STAID: A Self‐Refining Deep Learning Framework for Spatial Cell‐Type Deconvolution with Biologically Informed Modeling

Advanced Science, EarlyView.
STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu, Shuli Sun, Zhengliang Lv, Xinyu Liu, Yihua Wang, Bingqiang Liu   +5 more
wiley   +1 more source

Treatment of urethral strictures in transmasculine patients

, 2021
Background. Urethral strictures are a common complication after genital gender-affirming surgery (GGAS) in transmasculine patients. Studies that specifically focus on the management of urethral strictures are scarce.
Waterschoot, Mieke, Wietse Claeys, Waterloos, Marjan, Marlon Buncamper, Nicolaas Lumen, Michel Wirtz, Buncamper, Marlon, Wirtz, Michel, Lumen, Nicolaas, Marjan Waterloos, Mieke Waterschoot, Verla, Wesley, Wesley Verla, Claeys, Wietse, Piet Hoebeke, Hoebeke, Piet   +15 more
core   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

Advanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu, Nengsheng Fu, Zhongxin Huang, Yu Mou, Ensi Ma, Xiaoshi Wang, Tian Dong, Yujun Zhang, Danqing Liu, Di Jiang, Jingya Kuang, Rui Liao, Yifeng Tao, Leida Zhang, Chengcheng Zhang   +14 more
wiley   +1 more source

Chemokine receptor-5Delta32 mutation is no risk factor for ischemic-type biliary lesion in liver transplantation [PDF]

, 2009
It has been shown that certain chemokine receptor polymorphisms may correspond to certain complications after organ transplantation. Ischemic-type biliary lesion (ITBL) encounters for major morbidity and mortality in liver transplant recipients.
Christian Moench, Mönch, Christian, Peter Neuhaus, Christoph Heidenhain, Gero Puhl, Anja Lautem, Puhl, Gero, Neuhaus, Peter, Lautem, Anja, Heidenhain, Christoph   +9 more
core   +1 more source

Management of Panurethral Stricture

Urologic Clinics of North America, 2016
Panurethral stricture, involving the penile and bulbar urethra, is seen across the world .It is a complex disease with a relative paucity of literature on the subject. In India, Lichen Sclerosus is the most common cause of panurethral stricture followed by iatrogenic causes.
S. Kulkarni, P. Joshi, S. Surana, A. Hamouda   +3 more
openaire   +4 more sources

Association of a Multimodal Perioperative Care Program With Postoperative Complications in Elderly Patients Undergoing Gastrectomy for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
Implementation of a multimodal perioperative care program and reduction of postoperative complications. ABSTRACT Purpose This retrospective study aimed to assess the clinical effectiveness of a multimodal perioperative care program in reducing postoperative complications in elderly patients undergoing gastrectomy for gastric cancer.
Keiichi Fujiya, Hiroshi Fuseya, Yusuke Yonenaga, Keiko Sanada, Toshimi Inano, Yumi Oguma, Kazuko Nakajima, Chikako Ando, Kumiko Oka, Yusuke Koseki, Kenichiro Furukawa, Yutaka Tanizawa, Masanori Terashima, Etsuro Bando   +13 more
wiley   +1 more source

Biodegradable esophageal stents in benign and malignant strictures – a single center experience

Endoscopy International Open, 2016
Background and study aims: Biodegradable (BD) esophageal stents were recently developed mainly for refractory benign strictures, but experience and available literature are limited. Patients and methods: This was a retrospective observational
Dimitrios E. Sigounas, Sandeep Siddhi, John N. Plevris   +2 more
doaj   +1 more source

Reply to Strictures on 'Stricture of Urethra' [PDF]

The Boston Medical and Surgical Journal
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openaire   +2 more sources

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

Annals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata, Tetsuya Tajima, Satoshi Ogiso, Shinji Uemoto, Etsuro Hatano   +4 more
wiley   +1 more source