Results 41 to 50 of about 31,897 (243)

Acute responses to repeated sprints on a non-motorized treadmill on dominant- and non-dominant leg sprint parameters

open access: yesPhysical Education of Students, 2023
Background and Study Aim. The aim of this study was to examine the acute responses to repeated sprints on a non-motorized treadmill on dominant leg (DL) and non-dominant leg (NDL) sprint parameters. Material and Methods. Volunteered students from Sports
Mehmet Kale   +3 more
doaj   +1 more source

Gait in Huntington's disease and the stride length-cadence relationship. [PDF]

open access: yesBMC Neurol, 2014
The progressive deterioration of gait in Huntington's disease (HD) leads to functional decline and loss of function. To understand the underlying mechanisms responsible for the gait changes in HD, we examined the automatic control of gait by measuring the relationship between stride length and cadence.
Danoudis M, Iansek R.
europepmc   +4 more sources

Gait changes in a line of mice artificially selected for longer limbs [PDF]

open access: yesPeerJ, 2017
In legged terrestrial locomotion, the duration of stance phase, i.e., when limbs are in contact with the substrate, is positively correlated with limb length, and negatively correlated with the metabolic cost of transport.
Leah M. Sparrow   +5 more
doaj   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Effect of Knee Osteoarthritis Severity on Spatiotemporal Parameters of the Female Gait: a Pilot Study

open access: yesمجله پژوهش در علوم توانبخشی, 2014
Objective: Knee osteoarthritis (KOA) is one of the most common age related joint diseases. Various grades of KOA lead to change in gait pattern by different compensatory mechanisms. The aim of current study was to determine how KOA severities will affect
Zohreh Shafizadegan   +3 more
doaj   +1 more source

Abnormal gait pattern emerges during curved trajectories in high-functioning Parkinsonian patients walking in line at normal speed. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Several patients with Parkinson´s disease (PD) can walk normally along straight trajectories, and impairment in their stride length and cadence may not be easily discernible.
Anna Maria Turcato   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Thoracic limb stride length is associated with cognitive impairment in aging dogs

open access: yesFrontiers in Veterinary Science
IntroductionChanges in stride length have been linked to cognitive impairment in humans with dementia. In aging dogs, cognitive decline is accompanied by slower gait speed.
Shaghayegh Rafatpanah Baigi   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Stride length regulation in Parkinson's disease [PDF]

open access: yesBrain, 1996
Results of our previous studies have shown that the slow, shuffling gait of Parkinson's disease patients is due to an inability to generate appropriate stride length and that cadence control is intact and is used as a compensatory mechanism. The reason for the reduced stride length is unclear, although deficient internal cue production or inadequate ...
M E, Morris   +3 more
openaire   +2 more sources

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