Results 21 to 30 of about 1,603 (235)

An Analysis of Factors Affecting the Creation of Tension and Chaos among Nurses (Case Study: Public and Private Hospitals of Yazd Province)

Journal of Community Health Research, 2019
Introduction: Tension and chaos are considered as a socioeconomic phenomenon that can have adverse effects on individuals, organizations, and the community if not properly managed.
Gholamreza Bordbar, Reza Ebrahimzadeh Pezeshki   +1 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The right to strike as a collective right of employees

XXI međunarodni naučni skup „Pravnički dani - Prof. dr Slavko Carić“, Odgovori pravne nauke na izazove savremenog društva - zbornik radova
Collective labor law, among other things, also includes instruments for solving collective labor disputes, such as: mediation, arbitration and strike as a last resort to fulfill the demands of employees. As one of the instruments for solving collective labor disputes, a strike is a collective interruption of the work of employees, which is organized ...
Sanja Škorić, Tamara Čičovački
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The Impact of Labour Union Fragmentation on Service Delivery in The South African Public Sector

Journal of Governance and Administrative Reform
This study examines the impact of increasing fragmentation among labor unions in South Africa’s public sector on the government’s capacity to deliver services effectively.
Tando Rulashe, Ayanda Jam
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

ECONOMIC CAUSES OF LABOUR CONFLICTS IN THE NIGERIAN PUBLIC SECTOR: THE RESOLUTION AND THE STRATEGIES

International Studies Journal
This study examined the economic causes of labour conflicts in the Nigerian public sector, identifying critical issues such as inadequate salaries, delayed payments, poor working conditions, inflation, and lack of job security.
OIGIANGBE OMEAHON HENRY, COLLINS AKAHOMHEN, OKONOBOH ORIABURE WEDNESDAY, ISIRAOJIE LAWRENCE, IRABOR EHIKIOYA FESTUS   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Philosophical realignment of nursing workforce unionization and strike inceptions in the modern healthcare era

Journal of Healthcare Administration
The evolving global healthcare industry is defined by structural shifts toward collective action, as reflected in growing interest in nursing workforce unionization and strikes.
Simon Paul P. Navarro
doaj   +1 more source