Results 41 to 50 of about 583,596 (264)
Les grèves d’étudiants au quartier latin au temps de François Villon
Les Cahiers de Framespa, 2019 A corps united by age, sex, and awareness of its higher intellectual status, the Medieval University demonstrated a strong attachment to its privileges. This spirit was coupled with real independence, dearly acquired against the municipal, ecclesiastical,
Sophie Brouquet
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Are Trade Unions and Their Members “Populist”?
IdeAs, 2019 If in contemporary parlance “populism” stands for a social or political movement embodying otherwise unorganized and atomized anti-elite sentiment, then trade unionism is not populist.
Nelson Lichtenstein
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Toronto Civic Workers Bargaining Without a Base: The Significance of 2012
Studies in Social Justice, 2014 This article explores how the politics and economics of austerity has influenced collective bargaining between the CUPE Locals 79/416 and the city of Toronto.
Carlo Fanelli
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Socio, 2018 Like most countries of the world, Senegal experienced a student and trade-union protest in May 1968. From a student revolt at the University of Dakar, the 18th French university, the movement, which extended to high school students and workers’ unions ...
Omar Gueye
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Samples of counter-union campaign materials Leonard Scott & Company has used in recent Chicago area assignments, 1980 [PDF]
, 1980 Do and Don\u27t\u27s; Guarantee Sheet; Benefits; Negotiations; Strikes; One on One themes; General; Union ...
Scott, Leonard C
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source