Results 161 to 170 of about 35,764 (255)

Proteomic profiling of brain organoids and extracellular vesicles identifies early Alzheimer's disease biomarkers and drug response heterogeneity. [PDF]

Alzheimers Dement
Boyd RJ, Dong D, Sagar R, Iliuk A, Ahmed W, Androni X, Porsteinsson AP, Rosenberg PB, Lyketsos CG, Witwer KW, Mahairaki V.   +10 more
europepmc   +1 more source

MolMiner: Toward Controllable, Three‐Dimensional‐Aware, Fragment‐Based Molecular Design

Advanced Intelligent Discovery, EarlyView.
MolMiner is a fragment‐based, geometry‐aware, and order‐agnostic generative model for molecular design with strong inductive biases. Using symmetry‐aware fragment assembly, dynamic three‐dimensional geometry, and multi‐property conditioning, MolMiner enables interpretable and controllable molecular generation.
Raul Ortega‐Ochoa, Tejs Vegge, Jes Frellsen   +2 more
wiley   +1 more source

Precision Medicine Gene Network Analyser: part I-cancer driver gene identification through network topology and ensemble machine learning. [PDF]

Genomics Inform
Siddalingappa R, Hussain S, S D, Dheerendra P, Gornale S, B L M, Kothandan G.   +6 more
europepmc   +1 more source

A Two‐Stage Characterization Pipeline and Open‐Source Framework for Reproducible Tactile Sensing

Advanced Intelligent Systems, EarlyView.
The same soft tactile sensor returns different numbers when embodied in different robots. This is an Embodiment Gap that no shared framework currently captures transparently. A two‐stage characterization pipeline, paired with a FAIR open‐source digital datasheet, decouples intrinsic sensor behavior from embodiment effects and condenses cross‐laboratory
Matteo Lo Preti, Weng Buxiu, Petr Trunin, Muhammad Sunny Nazeer, Lucia Beccai, Perla Maiolino, Cecilia Laschi   +6 more
wiley   +1 more source

Minimally invasive capsule-string device enables spatially resolved microbiome profiling across the upper gastrointestinal tract. [PDF]

Gut Microbes
Garvey K, Harris JK, Furuta GT, Occhipinti KA, Wagner BD, Fernandez J, VeDepo M, Fouquier J, Hill EB, Robertson CE, Ackerman S, Shandas R.   +11 more
europepmc   +1 more source

Ising Solver Using Vertical NAND Flash Memory

Advanced Intelligent Systems, EarlyView.
Commercial V‐NAND flash memory is repurposed as a discrete‐time Ising solver by exploiting in‐memory current summation and read‐voltage‐controlled intrinsic noise. The system implements Hopfield neural‐network updates with simulated‐annealing‐like behavior, solving max‐cut problems with high accuracy and energy efficiency while using mass‐produced ...
Sung‐Ho Park, Yeongheon Yang, Jong‐Won Back, Jiseong Im, Ryun‐Han Koo, Jonghyun Ko, Dongseok Kwon, Jong‐Ho Lee   +7 more
wiley   +1 more source

Correction: Wang et al. TFRC Ablation Induces Insufficient Cartilage Development Through Mitochondrial p53 Translocation-Mediated Ferroptosis. <i>Int. J. Mol. Sci.</i> 2025, <i>26,</i> 2724. [PDF]

Int J Mol Sci
Wang Y, Wen X, Guo Y, Wang Y, Gu Y.
europepmc   +1 more source

Mechanistic investigation of Liujing Toutong tablet in the treatment of cerebral ischemia–reperfusion injury in rats by the integration of serum pharmacochemistry and metabolomics

Animal Models and Experimental Medicine, EarlyView.
The research strategy for pharmacodynamics, serum pharmacochemistry, metabolomics, and network pharmacology analysis method in intervention effects of LTT are illustrated. Abstract Background Liujing Toutong tablet (LTT) is a traditional Chinese patent medicine.
Zihan Yu, Ke Pei, Xiulin Wang, Wenling Li, Hongchang Li, Wangyang Xie, Xianglong Meng, Tingting Zhao, Yan Ning, Haixin Liu, Wenbin He   +10 more
wiley   +1 more source

A Dataset of Fatigue Properties for Welded Joints. [PDF]

Sci Data
Deng C, Luo C, Gong B, Liu Y, Zhang Z, Wang S, Zhang X.   +6 more
europepmc   +1 more source

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li, Guiying Shi, Jiaming Tang, Yiying Huang, Jie Wang, Xuepei Lei, Lin Bai   +6 more
wiley   +1 more source