Results 51 to 60 of about 458,083 (347)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Noncommutative Gauge Dynamics From The String Worldsheet [PDF]
, 2000 We show how string theory can be used to reproduce the one-loop two-point photon amplitude in noncommutative U(1) gauge theory. Using a simple realization of the gauge theory in bosonic string theory, we extract from a string cylinder computation in the ...
Gomis, Jaume +4 more
core +2 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Light strings and strong coupling in F-theory
Journal of High Energy Physics, 2023 We consider 4d N $$ \mathcal{N} $$ = 1 theories arising from F-theory compactifications on elliptically-fibered Calabi-Yau four-folds and investigate the non-perturbative structure of their scalar field space beyond the large volume/large complex ...
Max Wiesner
doaj +1 more source
On String Field Theory and Effective Actions
, 1992 A truncation of string field theory is compared with the duality invariant effective action of $D=4, N=4$ heterotic strings to cubic order. The three string vertex must satisfy a set of compatibility conditions.
Ademollo +45 more
core +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
KLT factorization of nonrelativistic string amplitudes
Journal of High Energy Physics, 2022 We continue our study of the Kawai-Lewellen-Tye (KLT) factorization of winding string amplitudes in [1]. In a toroidal compactification, amplitudes for winding closed string states factorize into products of amplitudes for open strings ending on an array
Ziqi Yan, Matthew Yu
doaj +1 more source
A Novel String Field Theory Solving String Theory by Liberating Left and Right Mover [PDF]
, 2013 We put forward ideas to a novel string field theory based on making some "objects" that essentially describe "liberated" left- and right- mover fields $X^{\mu}_{L}(\tau + \sigma)$ and $X^{\mu}_{R}(\tau - \sigma)$ on the string.
Nielsen, Holger B., Ninomiya, Masao
core +2 more sources
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Light-cone reduction of Witten’s open string field theory
Journal of High Energy Physics, 2019 We elucidate some exact relations between light-cone and covariant string field theories on the basis of the homological perturbation lemma for A ∞.
Hiroaki Matsunaga
doaj +1 more source