Results 111 to 120 of about 43,429 (313)
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
Advanced Science, EarlyView.NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Supersymmetric AdS$$_2\times \Sigma _2$$ 2×Σ2 solutions from tri-sasakian truncation
European Physical Journal C: Particles and Fields, 2017 A class of $$\mathrm{AdS}_2\times \Sigma _2$$ AdS2×Σ2 , with $$\Sigma _2$$ Σ2 being a two-sphere or a hyperbolic space, solutions within four-dimensional $$N=4$$ N=4 gauged supergravity coupled to three-vector multiplets with dyonic gauging is identified.
Parinya Karndumri
doaj +1 more source
Spacetime in string theory [PDF]
New Journal of Physics, 2005 We give a brief overview of the nature of spacetime emerging from string theory. This is radically different from the familiar spacetime of Einstein's relativity. At a perturbative level, the spacetime metric appears as ``coupling constants" in a two dimensional quantum field theory.
openaire +2 more sources
Advanced Science, EarlyView.CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong +5 more
wiley +1 more source
International Journal of Modern Physics A, 2015 Perhaps the most important way string theory has affected the perspective of particle physics phenomenology is through the "string theory landscape". We discuss the evidence supporting its existence, describe the regions of the landscape that have been explored, and examine what the string theory landscape might imply for most Standard Model problems.
openaire +5 more sources
Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
Advanced Science, EarlyView.As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Semi-Abelian gauge theories, non-invertible symmetries, and string tensions beyond N-ality [PDF]
, 2021 Mendel Nguyen +2 more
openalex +1 more source
Advanced Science, EarlyView.Senescent bone marrow mesenchymal stem cells (BMSCs) exhibit increased sensitivity to ferroptosis, a phenomenon associated with Steap4, a nicotinamide adenine dinucleotide phosphate hydrogen (NADPH)‐dependent metalloreductase that reduces Fe3+ to Fe2+.
Liangliang Wang +9 more
wiley +1 more source