Results 111 to 120 of about 6,660,767 (299)

The Kerr-Schild double copy in curved spacetime

open access: yesJournal of High Energy Physics, 2017
The double copy is a much-studied relationship between scattering amplitudes in gauge and gravity theories, that has subsequently been extended to classical field solutions.
Nadia Bahjat-Abbas   +2 more
doaj   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

open access: yesAdvanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino   +7 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Biadjoint wires

open access: yesPhysics Letters B, 2019
Biadjoint scalar field theory has been the subject of much recent study, due to a number of applications in field and string theory. The catalogue of exact non-linear solutions of this theory is relatively unexplored, despite having a role to play in ...
Nadia Bahjat-Abbas   +2 more
doaj   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

open access: yesAdvanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo   +40 more
wiley   +1 more source

Non-Riemannian geometry of M-theory

open access: yesJournal of High Energy Physics, 2019
We construct a background for M-theory that is moduli free. This background is then shown to be related to a topological phase of the E8(8) exceptional field theory (ExFT).
David S. Berman   +2 more
doaj   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

open access: yesAdvanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat   +6 more
wiley   +1 more source

Two-loop scattering amplitudes: double-forward limit and colour-kinematics duality

open access: yesJournal of High Energy Physics, 2019
We propose new formulae for the two-loop n-point D-dimensional integrands of scattering amplitudes in Yang-Mills theory and gravity. The loop integrands are written as a double-forward limit of tree-level trivalent diagrams, and are inferred from the ...
Yvonne Geyer   +2 more
doaj   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source

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