Results 141 to 150 of about 59,192 (316)
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Aspects of finite temperature corrections in string theory
PhDIn this thesis some aspects of temperature corrections in string theory are analyzed: in particular, we study the thermal contributions to the 4 dimensional effective potential arising from string theory compactifications.
Calo, Vincenzo
core
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Latex 60 pages, 2 figures, uses svmult.cls. Contribution to the volume "String theory and fundamental interactions", dedicated to Gabriele Veneziano on his 65th birthday.
openaire +2 more sources
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang +6 more
wiley +1 more source
Ramanujan's influence on string theory, black holes and moonshine. [PDF]
Harvey JA.
europepmc +1 more source
Perhaps the most important way string theory has affected the perspective of particle physics phenomenology is through the "string theory landscape". We discuss the evidence supporting its existence, describe the regions of the landscape that have been explored, and examine what the string theory landscape might imply for most Standard Model problems.
openaire +5 more sources
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
The shadow of dark matter as a shadow of string theory: string origin of the dipole term. [PDF]
Dick R.
europepmc +1 more source
This work proposed a pollen‐enhanced bionic mechanoreceptor based on ionic convection. Leveraging the ion anchoring effect of the pollen particle, the output performance could be ∼12 times higher than the original state. By employing deep learning models as AI brains, the feasibility of a sensory‐augmented prosthesis consisting of a pollen‐enhanced ...
Zi Hao Guo +7 more
wiley +1 more source

