Results 171 to 180 of about 5,534,446 (330)

The birth of string theory: Introduction and synopsis [PDF]

open access: yes, 2012
This is a draft of the introduction to the collective volume "The birth of string theory" (CUP, 2012), including the book's index and preface. The book explores the history of the theory’s early stages of development, as told by its main protagonists. It
Cappelli, Andrea   +3 more
core  

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Aspects of plane waves and Taub-NUT as exact string theory solutions [PDF]

open access: yes, 2004
This thesis is a study of some aspects of string theory solutions that are exact in the inverse string tension ɑ', and thus are valid beyond the low-energy limit.
Svendsen, Harald Georg
core  

New Janus interfaces from four-dimensional $$N=3$$ N = 3 gauged supergravity

open access: yesEuropean Physical Journal C: Particles and Fields
We construct new supersymmetric Janus solutions from four-dimensional $$N=3$$ N = 3 gauged supergravity coupled to eight vector multiplets with $$SO(3)\times SU(3)$$ S O ( 3 ) × S U ( 3 ) gauge group.
Parinya Karndumri
doaj   +1 more source

Lithium Niobate Electro‐Optic Photonic Processor for Variational Quantum Eigensolver

open access: yesAdvanced Science, EarlyView.
An integrated lithium‐niobate‐on‐insulator ququart processor implements an electro‐optically controlled photonic variational quantum eigensolver using single photons encoded in four path modes. Bell‐basis‐emulating ququart projective measurements reduce measurement settings while achieving chemical‐accuracy‐level molecular‐energy estimation.
Jinil Lee   +11 more
wiley   +1 more source

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

open access: yesAdvanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang   +11 more
wiley   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

open access: yesAdvanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang   +12 more
wiley   +1 more source

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