Results 121 to 130 of about 18,552 (304)

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

open access: yesAdvanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu   +11 more
wiley   +1 more source

Worldsheet formalism for decoupling limits in string theory

open access: yesJournal of High Energy Physics
We study the bosonic sector of a decoupling limit of type IIA superstring theory, where a background Ramond-Ramond one-form is fined tuned to its critical value, such that it cancels the associated background D0-brane tension.
Joaquim Gomis, Ziqi Yan
doaj   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li   +13 more
wiley   +1 more source

Finite temperature Casimir effect for a spinor field in cosmic dispiration spacetime

open access: yesJournal of High Energy Physics
This study explores the finite temperature Casimir effect for a massive spinor field in cosmic dispiration spacetime, formed by the combination of a cosmic string and a screw dislocation, using the generalized zeta function regularization method.
Joás Venâncio   +2 more
doaj   +1 more source

Regge limit of one-loop string amplitudes

open access: yesSciPost Physics
We study the high-energy limit of $2 \to 2$ one-loop string amplitudes at fixed momentum transfer. For the closed string, the high-energy behavior of the amplitudes can be determined from Regge theory just like in field theory, as was first discussed by ...
Pinaki Banerjee, Lorenz Eberhardt, Sebastian Mizera
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

open access: yesAdvanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu   +8 more
wiley   +1 more source

A Novel Linear Circuit For Current Equalization In Led Strings

open access: yesEletrônica de Potência, 2013
This paper deals with the problem of current sharing in parallel strings of LEDs. As there is no guarantee that the string voltages are the same, some strategy for equalizing their currents must be used.
Cláudio R. B. S. Rodrigues   +4 more
doaj   +1 more source

Topological aspects of string theories

open access: yesNuclear Physics B, 1987
In previous work, a new action principle for strings and superstrings in arbitrary dimensions was developed. It led to a classification of strings similar to the classification of point particles as massive, massless and tachyonic. Topological aspects of four-dimensional strings were also investigated.
A. P. BALACHANDRAN   +3 more
openaire   +3 more sources

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

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