Results 61 to 70 of about 168,533 (255)
Beyond Traditional Lateral Flow Assays: Enhancing Performance Through Multianalytical Strategies
BiosensorsMultiplex lateral flow assays are one of the greatest advancements in the world of rapid diagnostics, achieving the performance of several tests in one.
Eleni Lamprou +2 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Remarks on the Moser–Trudinger inequality
Advances in Nonlinear Analysis, 2013 We extend the Moser–Trudinger ...
Battaglia Luca, Mancini Gabriele
doaj +1 more source
CoRR, 2020 Presented to Genplan 2020 workshop, held in the AAAI 2020 conference (https://sites.google.com/view/genplan20) (2021/03/05: included missing acknowledgments)
Suárez Hernández, Alejandro +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Stripovska obravnava češkega narodnega preroda (problem Václava Hanke)
Slavistična Revija, 2014 Študija raziskuje stripovsko knjigo Šifra mistra Hanky ( Hankova šifra ) s poudarkom na deležu dokumentarnih sestavin in fikcije v zgodbi. Usmerjena je v vlogo Václava Hanke in Josefa Dobrovskega kot postav v tej zgodbi.
Eva Niklesová
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Multi-mode control of strip-finishing-temperature in hot-strip mills
工程科学学报, 2019 At present, hot-rolled strip manufacturing has gradually exhibited more diversity and process complexity. Using the single control strategy, the traditional strip-finishing temperature-control mode shows some defects and deficiencies, for example, low ...
WANG Hai-yu +5 more
doaj +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source