Results 71 to 80 of about 307,464 (285)

STRIPS Action Discovery

open access: yesCoRR, 2020
Presented to Genplan 2020 workshop, held in the AAAI 2020 conference (https://sites.google.com/view/genplan20) (2021/03/05: included missing acknowledgments)
Suárez Hernández, Alejandro   +3 more
openaire   +4 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Sanjad-Sakati syndrome with corneal opacity in a Palestinian neonate: case report

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2020
Sanjad-Sakati syndrome is an autosomal recessive disorder found mainly in people of Arabian origin. This is a report of a Palestinian premature (35 weeks gestation) newborn who was part of twins and had this rare disease.
Allam Fayez Abuhamda   +1 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The impact of melt-conditioned twin-roll casting on the downstream processing of an AZ31 magnesium alloy [PDF]

open access: yes, 2011
Copyright @ 2012 Springer VerlagMelt conditioning by intensive shear was used prior to twin-roll casting of AZ31 magnesium alloy strip to promote heterogeneous nucleation and to provide a refined and uniform microstructure without severe macrosegregation.
S. Pawar   +17 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Investigation on a Microextrusion Process of Parallel Protrusions from Metal Strip [PDF]

open access: yes, 2013
The continuous purchase of higher quality standards in the production with parallel reduction of the costs leads to the need of a robust process design avoiding as much as possible the occurrence of defects in the production.
Merklein, Marion   +2 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

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