Results 71 to 80 of about 407,274 (292)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Evaluation of Bearing Capacity of Strip Footing Using Random Layers Concept

Studia Geotechnica et Mechanica, 2015
The paper deals with evaluation of bearing capacity of strip foundation on random purely cohesive soil. The approach proposed combines random field theory in the form of random layers with classical limit analysis and Monte Carlo simulation.
Kawa Marek, Łydżba Dariusz
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Pseudoholomorphic strips in symplectizations II: Fredholm theory and transversality

Communications on Pure and Applied Mathematics, 2003
AbstractThis paper is part of a larger program, the investigation of the chord problem in three dimensional contact geometry. The main tool will be pseudoholomorphic strips in the symplectisation of a three dimensional contact manifold with two totally real submanifolds L0, L1 as boundary conditions.
openaire   +3 more sources

Comparison between Keller's and Ufimtsev's theories for the strip [PDF]

IEEE Transactions on Antennas and Propagation, 1971
The high-frequency backscattered far field produced by a plane electromagnetic wave obliquely incident on a perfectly conducting infinite strip is considered. A comparison is made between the results obtained by applying Keller's and Ufimtsev's asymptotic theories. It is shown that Ufimtsev's expansion is incorrect beyond the leading term, but that the
T. Senior, P. Uslenghi
openaire   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

The dual of non-extremal area: differential entropy in higher dimensions

Journal of High Energy Physics, 2020
The Ryu-Takayanagi formula relates entanglement entropy in a field theory to the area of extremal surfaces anchored to the boundary of a dual AdS space. It is interesting to ask if there is also an information theoretic interpretation of the areas of non-
Vijay Balasubramanian, Charles Rabideau
doaj   +1 more source

Defects in G/H coset, G/G topological field theory and discrete Fourier-Mukai transform

, 2011
In this paper we construct defects in coset $G/H$ theory. Canonical quantization of the gauged WZW model $G/H$ with $N$ defects on a cylinder and a strip is performed and the symplectomorphisms between the corresponding phase spaces and those of double ...
Alekseev, Alekseev, Bardakci, Blau, Brunner, Chu, Crnkovic, Crnkovic, Davydov, Di Francesco, Elitzur, Elitzur, Elitzur, Falceto, Fröhlich, Fuchs, Ganter, Gawedzki, Gawedzki, Gawedzki, Gawedzki, Gawedzki, Gawedzki, Gepner, Gepner, Gor Sarkissian, Graham, Kapustin, Kapustin, Karabali, Klimcik, Moore, Moore, Petkova, Petkova, Sarkissian, Sarkissian, Sarkissian, Schweigert, Spiegelglas, Witten, Witten, Witten   +42 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Finite-size corrections for universal boundary entropy in bond percolation

SciPost Physics, 2016
We compute the boundary entropy for bond percolation on the square lattice in the presence of a boundary loop weight, and prove explicit and exact expressions on a strip and on a cylinder of size $L$.
Jan de Gier, Jesper Lykke Jacobsen, Anita Ponsaing
doaj   +1 more source