Results 41 to 50 of about 3,119,905 (399)

Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody

open access: yesFluids and Barriers of the CNS, 2023
Background The blood brain barrier limits entry of macromolecular diagnostic and therapeutic cargos. Blood brain barrier transcytosis via receptor mediated transport systems, such as the transferrin receptor, can be used to carry macromolecular cargos ...
Thomas J. Esparza   +5 more
doaj   +1 more source

Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities.

open access: yesStroke, 2022
Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central nervous system. Structurally comprising the BBB, brain endothelial cells interact with pericytes, astrocytes, neurons, microglia, and perivascular macrophages ...
E. Candelario-Jalil   +2 more
semanticscholar   +1 more source

[Stroke].

open access: yesDer Radiologe, 2007
Today stroke represents a major medical and political problem in Western industrial nations. High demands need to be placed on the initial diagnostic work-up and therapeutic treatment to ensure that the patients benefit from the recent advancements achieved in diagnostic and therapeutic fields.
Ahlhelm, F   +6 more
openaire   +2 more sources

Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients [PDF]

open access: yes, 2015
Background and purpose: End stage renal disease (ESRD) requiring hemodialysis (HD) carries up to a 10-fold greater risk of stroke than normal renal function. Knowledge concerning risk factors and management strategies derived from the general population
Dawson, Jesse   +9 more
core   +1 more source

Is it a stroke? [PDF]

open access: yesBMJ, 2015
#### The bottom line Stroke is increasingly common and often fatal or disabling.1 The absence of a definitive diagnostic test for stroke and the potential for emergency interventions to restore brain perfusion,2 improve survival free of handicap, and minimise early recurrent stroke3 mean that doctors need to be able to diagnose acute stroke rapidly ...
David Blacker   +2 more
openaire   +2 more sources

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]

open access: yes, 2016
BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W.   +20 more
core   +2 more sources

Predicting Disability after Ischemic Stroke Based on Comorbidity Index and Stroke Severity—From the Virtual International Stroke Trials Archive-Acute Collaboration

open access: yesFrontiers in Neurology, 2017
Background and aimThe availability and access of hospital administrative data [coding for Charlson comorbidity index (CCI)] in large data form has resulted in a surge of interest in using this information to predict mortality from stroke.
Thanh G. Phan   +4 more
doaj   +1 more source

Use of the Neuroform Atlas stent for wide-necked cerebral aneurysms

open access: yesScientific Reports, 2023
To investigate the effect and safety of the Neuroform Atlas (NFA) stent in stent-assisted coiling of wide-necked intracranial aneurysms, patients with wide-necked intracranial aneurysms were retrospectively enrolled and treated with the NFA stent ...
Hui-Li Gao   +5 more
doaj   +1 more source

The relation between questions indicating transient ischaemic attack and stroke in 20 years of follow up in men and women in the Renfrew/Paisley Study [PDF]

open access: yes, 2001
<b>STUDY OBJECTIVE</b> Transient ischaemic attack (TIA) is often a precursor to stroke, so identification of people experiencing TIA could assist in stroke prevention by indicating those at high risk of stroke who would benefit most from ...
Davey Smith, G., Hart, C.L., Hole, D.J.
core   +2 more sources

Clinical Potential of Extracellular Vesicles in Type 2 Diabetes

open access: yesFrontiers in Endocrinology, 2021
Type 2 diabetes (T2D) is a major public health disease which is increased in incidence and prevalence throughout the whole world. Insulin resistance (IR) in peripheral tissues and insufficient pancreatic β-cell mass and function have been recognized as ...
Jie Liu   +18 more
doaj   +1 more source

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