Results 51 to 60 of about 1,296,100 (313)

Long-Term Changes in Post-Stroke Depression, Emotional Incontinence, and Anger [PDF]

, 2021
Background and purpose: Long-term changes in post-stroke depression (PSD), post-stroke emotional incontinence (PSEI), and post-stroke anger (PSA) have rarely been studied.
허지회
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Detection of C8/T1 radiculopathy by measuring the root motor conduction time

BMC Neurology, 2022
Background Root motor conduction time (RMCT) can noninvasively evaluate the status of the proximal root segment. However, its clinical application remains limited, and wider studies regarding its use are scarce.
Dougho Park, Sang-Eok Lee, Jae Man Cho, Joong Won Yang, Donghoon Yang, Mansu Kim, Heum Dai Kwon   +6 more
doaj   +1 more source

Clinical Potential of Extracellular Vesicles in Type 2 Diabetes

Frontiers in Endocrinology, 2021
Type 2 diabetes (T2D) is a major public health disease which is increased in incidence and prevalence throughout the whole world. Insulin resistance (IR) in peripheral tissues and insufficient pancreatic β-cell mass and function have been recognized as ...
Jie Liu, Jie Liu, Jie Liu, Xin Sun, Xin Sun, Fu-Liang Zhang, Fu-Liang Zhang, Hang Jin, Hang Jin, Xiu-Li Yan, Shuo Huang, Shuo Huang, Shuo Huang, Zhen-Ni Guo, Zhen-Ni Guo, Zhen-Ni Guo, Yi Yang, Yi Yang, Yi Yang   +18 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Magnetic resonance imaging to visualize stroke and characterize stroke recovery: a review

Frontiers in Neurology, 2013
The global burden of stroke continues to grow. Although stroke prevention strategies (eg. medications, diet and exercise) can contribute to risk reduction, options for acute interventions (eg. thrombolytic therapy for ischemic stroke) are limited to the
Bradley J MacIntosh, Bradley J MacIntosh, Simon J Graham, Simon J Graham   +3 more
doaj   +1 more source

Abstract 268: Validation of an automated method to assess 24‐hour infarct volume in stroke patients

Stroke: Vascular and Interventional Neurology, 2023
Introduction In stroke patients, accurate infarct volume assessment at 24 hours typically requires manual segmentation of lesions that often are not well defined.
Magda Jablonska, João André Sousa, Marc Molina, Pere Canals, Alvaro Garcia‐Tornel, Marc Rodrigo‐Gisbert, Federica Rizzo, Marta Olivé‐Gadea, Manuel Requena, David Rodriguez‐Luna, Noelia Rodriguez‐Villatoro, Jesús M. Juega, Marián Muchada, Jorge Pagola, Marta Rubiera, Alejandro Tomasello, Carlos A. Molina, Leonardo Tanzi, Victor Salvia, Cristian Marti, Marc Ribo   +20 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Comparison of Hemorrhage on CT Versus MRI After Thrombectomy: The HECATE Study

Stroke: Vascular and Interventional Neurology
Background The characterization of hemorrhage following acute stroke intervention has largely been computed tomography (CT) based. We sought to compare magnetic resonance imaging‐ (MRI‐) and CT‐based scoring of hemorrhage after acute endovascular therapy
Amie W. Hsia, Lawrence L. Latour, Sana Somani, Carolyn A. Lomahan, Yongwoo Kim, John K. Lynch, Marie Luby   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source