Results 151 to 160 of about 95,784 (257)

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Elucidating stroke etiology through lipidomics of thrombi and plasma in acute ischemic stroke patients undergoing endovascular thrombectomy. [PDF]

J Cereb Blood Flow Metab
Cheng CN, Lee CW, Lee CH, Tang SC, Kuo CH.   +4 more
europepmc   +1 more source

Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition. [PDF]

J Neurointerv Surg, 2021
Fitzgerald S, Rossi R, Mereuta OM, Jabrah D, Okolo A, Douglas A, Molina Gil S, Pandit A, McCarthy R, Gilvarry M, Dunker D, Nordanstig A, Ceder E, Redfors P, Jood K, Dehlfors N, Magoufis G, Tsivgoulis G, Brinjikji W, Kallmes DF, O'Hare A, Power S, Brennan P, Alderson J, Nagy A, Vadász Á, Psychogios K, Szikora I, Tatlisumak T, Rentzos A, Thornton J, Doyle KM.   +31 more
europepmc   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Development and validation of a blood biomarker-based model for differentiating stroke etiology in acute large vessel occlusion. [PDF]

Front Neurol
Gao W, Zhu R, She J, Huang R, Cai L, Jin S, Lin Y, Lin J, Chen X, Chen L.   +9 more
europepmc   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

StrokeClassifier: ischemic stroke etiology classification by ensemble consensus modeling using electronic health records. [PDF]

NPJ Digit Med
Lee HJ, Schwamm LH, Sansing LH, Kamel H, de Havenon A, Turner AC, Sheth KN, Krishnaswamy S, Brandt C, Zhao H, Krumholz H, Sharma R.   +11 more
europepmc   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source

Is Histologic Thrombus Composition in Acute Stroke Linked to Stroke Etiology or to Interventional Parameters? [PDF]

AJNR Am J Neuroradiol, 2020
Goebel J, Gaida BJ, Wanke I, Kleinschnitz C, Koehrmann M, Forsting M, Moenninghoff C, Radbruch A, Radbruch A, Junker A.   +9 more
europepmc   +1 more source

Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease

Journal of Clinical Ultrasound, EarlyView.
Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio, Maria Angelica Jungles Malikoski, Eduardo Henrique Bonotto, Sandra Monica Tochetto, Marco Stephan Lofrano‐Alves   +4 more
wiley   +1 more source