Results 51 to 60 of about 6,731,060 (306)

Quality of Acute Stroke Care at Primary Stroke Centers Before and After Certification in Comparison to Never-Certified Hospitals

open access: yesFrontiers in Neurology, 2020
Background and Purpose: Primary stroke center (PSC) certification is associated with improvements in stroke care and outcome. However, these improvements may reflect a higher baseline level of care delivery in hospitals eventually achieving certification.
Kristina Shkirkova   +12 more
doaj   +1 more source

The Royal Blackburn Hospital, Acute Stroke Unit [PDF]

open access: yes
Stroke Unit ...
Ramsden, Victoria, Philip, Sheeba J.
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The role of fasting versus nonfasting triglycerides in ischemicstroke: a systematic review

open access: yesFrontiers in Neurology, 2010
Objective: To synthesize results from pertinent studies and determine if fasting and/or nonfasting triglycerides are a risk factor for ischemic stroke.
Christopher Leonards   +7 more
doaj   +1 more source

Abstract 1122‐000163: Stroke Center Accessibility Study in the U.S. Using Geospatial Analysis and Machine Learning

open access: yesStroke: Vascular and Interventional Neurology, 2021
Introduction: Background: Several accrediting bodies certify the level of stroke care hospitals provide. The Joint Commission on Hospital Accreditation (JC) is the largest accrediting body in the United States.
Ahsan Ali, Randall Edgell
doaj   +1 more source

The challenge of acute-stroke management: does telemedicine offer a solution? [PDF]

open access: yes, 2006
<p><b>Background:</b> Several studies have described successful experiences with the use of telemedicine in acute stroke. The objective of this study was to assess the feasibility, acceptability, and treatment delivery reliability, of ...
Langhorne, P., Wu, O.
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

High-sensitivity C-reactive protein as a better predictor of post-thrombolytic functional outcome in patients with previous antiplatelet therapy

open access: yesEuropean Journal of Medical Research, 2022
Background C-reactive protein (CRP) is an important biomarker of inflammation and plays a pivotal role in predicting the clinical prognosis of cardiovascular and cerebrovascular diseases.
Tan Li   +8 more
doaj   +1 more source

Stroke Center Characteristics Which Influence the Administration of Thrombolytic Therapy for Acute Ischemic Stroke: A National Survey of Stroke Centers in Taiwan

open access: yes, 2010
Stroke centers and intravenous tissue plasminogen activators (tPA) are effective management for acute ischemic stroke. This study aimed to analyze stroke center characteristics on the administration of thrombolytic therapy.
JENG, JIANN-SHING;TANG, SUNG-CHUN;TSAI, LI-KAI;YEH, SHIN-JOE;YIP, PING-KEUNG   +1 more
core   +1 more source

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